Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 10/20 | 0.94 |
| ▸ | MAPT | P10636 | 7/20 | 0.94 |
| ▸ | GAA | P10253 | 6/20 | 0.94 |
| ▸ | MEN1 | O00255 | 3/20 | 0.94 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.94 |
| ▸ | BCHE | P06276 | 3/20 | 0.94 |
| ▸ | ACHE | P22303 | 3/20 | 0.94 |
| ▸ | SNCA | P37840 | 3/20 | 0.94 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.94 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.94 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.94 |
| ▸ | POLB | P06746 | 1/20 | 0.94 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.94 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.94 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.94 |
| ▸ | MAOA | P21397 | 1/20 | 0.94 |
| ▸ | CNR1 | P21554 | 1/20 | 0.94 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.94 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.94 |
| ▸ | HTR2C | P28335 | 1/20 | 0.94 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenothiazine SCHEMBL9425030 | 1.00 | NOX1 (0.94) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL29022242 | 0.97 | NOX1 (0.90) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL29352248 | 0.97 | NOX1 (1.00) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL2504207 | 0.97 | NOX1 (1.00) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL9114 | 0.97 | NOX1 (1.00) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL29349533 | 0.97 | NOX1 (1.00) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL6315328 | 0.97 | NOX1 (1.00) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL23683396 | 0.94 | NOX1 (0.94) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL22467844 | 0.94 | NOX1 (0.94) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL1470990 | 0.94 | NOX1 (0.94) | NOX1MAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4385512-A1 | OPTIMISED DOSAGE OF DIAMINOPHENOTHIAZINES IN POPULATIONS | WisTa Laboratories Ltd. (SG) | 2024-06-19 | — | — | EP | disclosed |
| EP-4364801-A2 | OPTIMISED DOSAGE OF DIAMINOPHENOTHIAZINES IN POPULATIONS | WisTa Laboratories Ltd. (SG) | 2024-05-08 | — | — | EP | disclosed |
| CN-111556750-B | Agent for improving mitochondrial dysfunction and preventive or therapeutic agent for diseases or symptoms caused by mitochondrial dysfunction and use thereof | 学校法人自治医科大学 | 2023-05-26 | — | — | CN | disclosed |
| US-20230115931-A1 | OPTIMISED DOSAGE OF DIAMINOPHENOTHIAZINES IN POPULATIONS | WISTA LABORATORIES LTD. (SG) | 2023-04-13 | — | — | US | disclosed |
| US-20210236509-A1 | OPTIMISED DOSAGE OF DIAMINOPHENOTHIAZINES IN POPULATIONS | WISTA LABORATORIES LTD. (GB) | 2021-08-05 | — | — | US | disclosed |
| EP-3826639-A1 | OPTIMISED DOSAGE OF DIAMINOPHENOTHIAZINES IN POPULATIONS | WisTa Laboratories Ltd. (SG) | 2021-06-02 | — | — | EP | disclosed |
| CN-111556750-A | Ameliorating agent for mitochondrial dysfunction, prophylactic or therapeutic agent for disease or symptom caused by mitochondrial dysfunction, and use thereof | 学校法人自治医科大学 | 2020-08-18 | — | — | CN | disclosed |
| WO-2020020751-A1 | OPTIMISED DOSAGE OF DIAMINOPHENOTHIAZINES IN POPULATIONS | WISTA LABORATORIES LTD. (SG) | 2020-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230115931-A1 | OPTIMISED DOSAGE OF DIAMINOPHENOTHIAZINES IN POPULATIONS | MAPT, TPMT, LMTK2 | NOX1 586/4885MAPT 1/4885GAA 1669/4885 |
| US-20210236509-A1 | OPTIMISED DOSAGE OF DIAMINOPHENOTHIAZINES IN POPULATIONS | MAPT, TPMT, LMTK2 | NOX1 586/4885MAPT 1/4885GAA 1669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.