Phenothiazine

Phenothiazine

SCHEMBL6315328

c1ccc2c(c1)Nc1ccccc1S2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 10/20 1.00
MAPT P10636 7/20 1.00
GAA P10253 6/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
BCHE P06276 3/20 1.00
ACHE P22303 3/20 1.00
SNCA P37840 3/20 1.00
ALOX15 P16050 3/20 1.00
TDP1 Q9NUW8 2/20 1.00
CYP1A2 P05177 2/20 1.00
POLB P06746 1/20 1.00
CYP3A4 P08684 1/20 1.00
ADORA3 P0DMS8 1/20 1.00
ALOX12 P18054 1/20 1.00
MAOA P21397 1/20 1.00
CNR1 P21554 1/20 1.00
PTGS1 P23219 1/20 1.00
SLC6A2 P23975 1/20 1.00
HTR2C P28335 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenothiazine SCHEMBL9114 1.00 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL29352248 1.00 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL29349533 1.00 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL2504207 1.00 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL23683396 0.97 NOX1 (0.94) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL22467844 0.97 NOX1 (0.94) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL1470980 0.97 NOX1 (0.94) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL22467847 0.97 NOX1 (0.94) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL21635186 0.97 NOX1 (0.94) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL1470990 0.97 NOX1 (0.94) NOX1MAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1330645-C Benzofuran-2-ones as colorants for organic materials CIBA SC HOLDING AG (CH) 2007-08-08 CN claimed
US-6872839-B1 Benzofuran-2-one CIBASPECIALTY CHEMICALS CORP. (US) 2005-03-29 US claimed
US-4155874-A AZINE DYES, DRUGS, CHARGE TRANSFER COMPLEXES WEST LABORATORIES, INC. (US) 1979-05-22 US claimed