Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5658273 | 0.86 | KDM4E (0.57) | KDM4EPOLBUSP2HSD17B10ALDH1A1 | |
| SCHEMBL2113203 | 0.86 | KDM4E (0.53) | KDM4EPOLBUSP2HSD17B10ALDH1A1 | |
| SCHEMBL644549 | 0.86 | KDM4E (0.56) | KDM4EPOLBUSP2HSD17B10ALDH1A1 | |
| SCHEMBL4302772 | 0.84 | LCK (0.59) | KDM4EPOLBHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL3979015 | 0.83 | KDM4E (0.57) | KDM4EPOLBUSP2HSD17B10ALDH1A1 | |
| SCHEMBL26660999 | 0.82 | MAPT (0.50) | KDM4EPOLBUSP2HSD17B10ALDH1A1 | |
| SCHEMBL28257934 | 0.82 | PTPN1 (0.57) | KDM4EPOLBUSP2HSD17B10ALDH1A1 | |
| SCHEMBL11929030 | 0.81 | KDM4E (0.69) | KDM4EPOLBUSP2HSD17B10ALDH1A1 | |
| SCHEMBL16163314 | 0.81 | SMN1; SMN2 (0.56) | KDM4EPOLBUSP2HSD17B10ALDH1A1 | |
| SCHEMBL16163313 | 0.81 | SMN1; SMN2 (0.56) | KDM4EPOLBUSP2HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020016389-A1 | THIOXANTHONE DERIVATIVES, COMPOSITION COMPRISING THE SAME AND PATTERN FORMING METHOD COMPRISING SAID COMPOSITION | LINTFIELD LIMITED (GB) | 2020-01-23 | — | — | WO | disclosed |