Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437132 | 0.85 | LCK (0.56) | KDM4EPOLBPTPN1HSD17B10ALDH1A1 | |
| SCHEMBL30740970 | 0.85 | LCK (0.56) | KDM4EPOLBPTPN1HSD17B10ALDH1A1 | |
| SCHEMBL12135968 | 0.84 | KDM4E (0.67) | KDM4EPOLBPTPN1HSD17B10USP2 | |
| SCHEMBL2113203 | 0.83 | KDM4E (0.53) | KDM4EPOLBPTPN1HSD17B10USP2 | |
| SCHEMBL21635979 | 0.83 | KDM4E (0.65) | KDM4EPOLBPTPN1HSD17B10USP2 | |
| SCHEMBL20328547 | 0.82 | KDM4E (0.56) | KDM4EPOLBPTPN1HSD17B10USP2 | |
| SCHEMBL5658273 | 0.80 | KDM4E (0.57) | KDM4EPOLBPTPN1HSD17B10USP2 | |
| SCHEMBL438401 | 0.80 | KDM4E (0.53) | KDM4EPOLBPTPN1HSD17B10USP2 | |
| SCHEMBL644549 | 0.79 | KDM4E (0.56) | KDM4EPOLBPTPN1HSD17B10USP2 | |
| Hydrochloric Acid SCHEMBL28974048 | 0.79 | KDM4E (0.55) | KDM4EPOLBHSD17B10USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |