SCHEMBL21636364

SCHEMBL21636364

Cc1cc(-c2ccccc2)nc(-c2cccc(-c3ccc(C#N)cc3)c2)n1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 7/20 0.55
MYC P01106 1/20 0.49
GABRA1 P14867 1/20 0.49
GABRG2 P18507 1/20 0.49
GABRB3 P28472 1/20 0.49
GABRA5 P31644 1/20 0.49
GABRA3 P34903 1/20 0.49
ALDH1A3 P47895 2/20 0.46
LMNA P02545 2/20 0.45
KDM4E B2RXH2 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
ABCB1 P08183 4/20 0.45
L3MBTL1 Q9Y468 1/20 0.43
MEN1 O00255 2/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
CYP2C19 P33261 2/20 0.42
KMT2A Q03164 2/20 0.42
CLK4 Q9HAZ1 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21636309 0.94 ABCG2 (0.59) ABCG2MYCGABRA1GABRG2GABRB3
SCHEMBL19164376 0.93 ABCG2 (0.63) ABCG2MYCGABRA1GABRG2GABRB3
SCHEMBL21636353 0.93 ABCG2 (0.63) ABCG2MYCGABRA1GABRG2GABRB3
SCHEMBL19164447 0.93 ABCG2 (0.63) ABCG2MYCGABRA1GABRG2GABRB3
SCHEMBL21636321 0.91 ABCG2 (0.64) ABCG2MYCGABRA1GABRG2GABRB3
SCHEMBL21636328 0.91 ABCG2 (0.64) ABCG2MYCGABRA1GABRG2GABRB3
SCHEMBL21636479 0.90 ABCG2 (0.57) ABCG2GABRA1GABRG2GABRB3GABRA5
SCHEMBL21636354 0.89 ABCG2 (0.60) ABCG2GABRA1GABRG2GABRB3GABRA5
SCHEMBL21636311 0.89 ABCG2 (0.60) ABCG2GABRA1GABRG2GABRB3GABRA5
SCHEMBL21031210 0.88 LMNA (0.51) ABCG2LMNAKDM4EL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020016233-A1 COMPOUND AND ORGANIC SEMICONDUCTING LAYER, ORGANIC ELECTRONIC DEVICE, DISPLAY DEVICE AND LIGHTING DEVICE COMPRISING THE SAME NOVALED GMBH (DE) 2020-01-23 WO disclosed