Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ALB | P02768 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.51 |
| ▸ | TYMP | P19971 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 8/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.38 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21539861 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAALBMAPK1P2RX3 | |
| SCHEMBL22990456 | 0.86 | ALDH1A1 (0.43) | ALDH1A1LMNAALBMAPK1P2RX3 | |
| SCHEMBL21417219 | 0.86 | ALDH1A1 (0.71) | ALDH1A1LMNAALBMAPK1P2RX3 | |
| SCHEMBL20327576 | 0.86 | ALDH1A1 (0.71) | ALDH1A1LMNAALBMAPK1P2RX3 | |
| SCHEMBL24320904 | 0.85 | ALDH1A1 (0.65) | ALDH1A1LMNAALBMAPK1P2RX3 | |
| SCHEMBL25057498 | 0.84 | ALDH1A1 (0.69) | ALDH1A1LMNAALBMAPK1P2RX3 | |
| SCHEMBL21417395 | 0.84 | ALDH1A1 (0.69) | ALDH1A1LMNAALBMAPK1P2RX3 | |
| SCHEMBL21132949 | 0.84 | ALDH1A1 (0.69) | ALDH1A1LMNAALBMAPK1P2RX3 | |
| SCHEMBL21539864 | 0.82 | ALDH1A1 (0.63) | ALDH1A1LMNAALBMAPK1P2RX3 | |
| SCHEMBL25057477 | 0.81 | ALDH1A1 (0.64) | ALDH1A1LMNAALBMAPK1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020016782-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN BIOTECH, INC. (US) | 2020-01-23 | — | — | WO | disclosed |