Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.42 |
| ▸ | TTK | P33981 | 9/20 | 0.38 |
| ▸ | KIT | P10721 | 4/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21638698 | 0.92 | BRD4 (0.43) | BRD4TTKKITABL1PIK3CA | |
| SCHEMBL21638663 | 0.89 | BRD4 (0.43) | BRD4KITPIK3CA | |
| SCHEMBL16721136 | 0.86 | BRD4 (0.48) | BRD4TTKKITPIK3CA | |
| SCHEMBL21638444 | 0.86 | BRD4 (0.47) | BRD4TTKKITPIK3CA | |
| SCHEMBL21674541 | 0.86 | BRD4 (0.49) | BRD4TTKKITABL1 | |
| SCHEMBL16722220 | 0.84 | BRD4 (0.55) | BRD4TTKKITPIK3CA | |
| SCHEMBL16721515 | 0.84 | BRD4 (0.55) | BRD4TTKKITPIK3CA | |
| SCHEMBL21638700 | 0.84 | BRD4 (0.51) | BRD4PIK3CD | |
| SCHEMBL21638653 | 0.83 | BRD4 (0.46) | BRD4TTKKITPIK3CA | |
| SCHEMBL16722521 | 0.83 | BRD4 (0.54) | BRD4TTKKITPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071205-B1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | FORMA THERAPEUTICS INC (US) | 2020-02-05 | — | — | EP | disclosed |