SCHEMBL21640022

SCHEMBL21640022

[CH2]C(F)(F)OCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9509371 0.72
SCHEMBL760157 0.72
SCHEMBL691901 0.72
SCHEMBL17729825 0.72
SCHEMBL14560639 0.72
SCHEMBL11185102 0.72
SCHEMBL6934795 0.69 CES2 (0.41)
SCHEMBL6547844 0.69
SCHEMBL128926 0.69
SCHEMBL2034670 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116710450-A Pyrrolo [3,2-b ] pyridine derivatives for the treatment of cGAS-related disorders 诺华股份有限公司 2023-09-05 CN claimed
CN-116635382-A Indole derivatives useful for treating cGAS-related disorders 诺华股份有限公司 2023-08-22 CN claimed
CN-110520422-B Novel pyridonecarboxylic acid derivative or salt thereof 涌永制药株式会社 2023-09-05 CN disclosed
US-20200062752-A1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 2020-02-27 US disclosed
EP-3604305-A1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF Wakunaga Pharmaceutical Co., Ltd. (JP) 2020-02-05 EP disclosed
CN-105074996-B Nonaqueous electrolytic solution and the electric energy storage device for having used the nonaqueous electrolytic solution 宇部兴产株式会社 2017-10-03 CN disclosed
CN-106455565-A Use of substituted oxotetrahydroquinoline sulfonamides or salts thereof for increasing stress tolerance in plants 拜耳作物科学股份公司 2017-02-22 CN disclosed