Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL6435305 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL16341729 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL7199331 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL10706022 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL128144 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL3942385 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL2291422 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL5667381 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL4351997 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL642599 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815066-B2 | Coating composition with phosphorous-containing resins and organometallic compounds | BASF COATINGS GMBH (DE) | 2014-08-26 | — | — | US | claimed |
| US-20110184119-A1 | Bismuth-Containing Catalytic System for Polymerising Polymers | KRONOS INTERNATIONAL, INC. (DE) | 2011-07-28 | — | — | US | claimed |
| US-12286350-B1 | Method for generating hydrogen using Bi2O3@SiO2 nanocomposite catalyst | IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) | 2025-04-29 | — | — | US | disclosed |
| US-11884837-B2 | Scratch and mar resistant automotive coatings | BASF COATINGS GMBH (DE) | 2024-01-30 | — | — | US | disclosed |
| EP-3655451-B1 | LOW TEMPERATURE CURING 1K BASECOAT AND METHOD TO COAT A SUBSTRATE WITH THE 1K BASECOAT | BASF COATINGS GMBH (DE) | 2023-04-12 | — | — | EP | disclosed |
| US-11583890-B2 | Low temperature curing 1K basecoat and method to coat a substrate with the 1K basecoat | BASF COATINGS GMBH (DE) | 2023-02-21 | — | — | US | disclosed |
| CN-110891993-B | Low temperature curing 1K basecoat and method for coating a substrate with a 1K basecoat | 巴斯夫涂料有限公司 | 2022-11-22 | — | — | CN | disclosed |
| US-11459483-B2 | Low temperature cure coating formed via polarity-facilitated catalyst migration between layers in a double layer curing mechanism | BASF COATINGS GMBH (DE) | 2022-10-04 | — | — | US | disclosed |
| CN-110945085-B | Low temperature cured coatings formed by polarity-promoted catalyst migration between layers in a two-layer cure mechanism | 巴斯夫涂料有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-109476811-B | One-part low temperature cure coating formed via a dual layer cure mechanism | 巴斯夫涂料有限公司 | 2022-02-11 | — | — | CN | disclosed |
| US-20210371693-A1 | TWO-COMPONENT (2K) CLEARCOAT AND METHOD TO COAT A SUBSTRATE WITH THE TWO-COMPONENT (2K) CLEARCOAT HAVING ENHANCED VISUAL APPEARANCE | BASF CORPORATION | 2021-12-02 | — | — | US | disclosed |
| US-20110184119-A1 | Bismuth-Containing Catalytic System for Polymerising Polymers | KRONOS INTERNATIONAL, INC. (DE) | 2011-07-28 | — | — | US | disclosed |
| WO-2010077901-A1 | ELECTROCOAT COMPOSITION AND PROCESS REPLACING PHOSPHATE PRETREATMENT | BASF COATINGS GMBH (US) | 2010-07-08 | — | — | WO | disclosed |
| US-20100167062-A1 | COATING COMPOSITION WITH PHOSPHOROUS-CONTAINING RESINS AND ORGANOMETALLIC COMPOUNDS | BASF CORPORATION (US) | 2010-07-01 | — | — | US | disclosed |
| EP-2043611-A2 | METAL-CONTAINING FORMULATIONS AND METHODS OF USE | Nucryst Pharmaceuticals Corp. (CA) | 2009-04-08 | — | — | EP | disclosed |
| US-20080050452-A1 | METAL-CONTAINING FORMULATIONS AND METHODS OF USE | NUCRYST PHARMACEUTICALS | 2008-02-28 | — | — | US | disclosed |
| US-20080044491-A1 | METAL-CONTAINING FORMULATIONS AND METHODS OF USE | NUCRYST PHARMACEUTICALS | 2008-02-21 | — | — | US | disclosed |
| US-20080014278-A1 | METAL-CONTAINING FORMULATIONS AND METHODS OF USE | NUCRYST PHARMACEUTICALS | 2008-01-17 | — | — | US | disclosed |
| US-20080014247-A1 | METAL-CONTAINING FORMULATIONS AND METHODS OF USE | NUCRYST PHARMACEUTICALS | 2008-01-17 | — | — | US | disclosed |
| WO-2008005705-A2 | METAL-CONTAINING FORMULATIONS AND METHODS OF USE | NUCRYST PHARMACEUTICALS CORP. (CA) | 2008-01-10 | — | — | WO | disclosed |