Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.59 |
| ▸ | PGR | P06401 | 3/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 14/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | TNF | P01375 | 1/20 | 0.58 |
| ▸ | IL6 | P05231 | 1/20 | 0.58 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
| ▸ | GLUL | P15104 | 1/20 | 0.58 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.58 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21641270 | 1.00 | HIF1A (0.59) | HIF1APGRNR3C1HSD17B10CYP3A4 | |
| SCHEMBL21641358 | 0.89 | CYP3A4 (0.60) | HIF1APGRNR3C1HSD17B10CYP3A4 | |
| SCHEMBL21641359 | 0.89 | CYP3A4 (0.60) | HIF1APGRNR3C1HSD17B10CYP3A4 | |
| SCHEMBL26181084 | 0.89 | CYP3A4 (0.60) | HIF1APGRNR3C1HSD17B10CYP3A4 | |
| SCHEMBL21641190 | 0.89 | KMT2A (0.58) | HIF1APGRNR3C1HSD17B10CYP3A4 | |
| SCHEMBL21641191 | 0.89 | KMT2A (0.58) | HIF1APGRNR3C1HSD17B10CYP3A4 | |
| SCHEMBL21641462 | 0.88 | HIF1A (0.58) | HIF1APGRNR3C1HSD17B10CYP3A4 | |
| SCHEMBL21641461 | 0.88 | HIF1A (0.58) | HIF1APGRNR3C1HSD17B10CYP3A4 | |
| SCHEMBL11040065 | 0.87 | NR3C1 (0.69) | HIF1APGRNR3C1HSD17B10CYP3A4 | |
| SCHEMBL7753162 | 0.87 | NR3C1 (0.69) | HIF1APGRNR3C1HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604322-B1 | LACTULOSE GLYCOSIDE COMPOUND AND PREPARATION METHOD AND USE THEREOF | FRUITHY HOLDINGS LTD (CN) | 2023-10-18 | — | — | EP | claimed |
| EP-3604322-A1 | LACTULOSE GLYCOSIDE COMPOUND AND PREPARATION METHOD AND USE THEREOF | FRUITHY HOLDINGS LIMITED (CN) | 2020-02-05 | — | — | EP | claimed |
| CN-110650966-A | Lactulose glycoside compound, preparation method and application thereof | 合肥合源药业有限公司 | 2020-01-03 | — | — | CN | claimed |
| EP-3604322-B1 | LACTULOSE GLYCOSIDE COMPOUND AND PREPARATION METHOD AND USE THEREOF | FRUITHY HOLDINGS LTD (CN) | 2023-10-18 | — | — | EP | disclosed |
| CN-110650966-B | Lactulose glycoside compound, preparation method and application thereof | 合肥合源药业有限公司 | 2022-06-21 | — | — | CN | disclosed |
| EP-3604322-A1 | LACTULOSE GLYCOSIDE COMPOUND AND PREPARATION METHOD AND USE THEREOF | FRUITHY HOLDINGS LIMITED (CN) | 2020-02-05 | — | — | EP | disclosed |
| CN-110650966-A | Lactulose glycoside compound, preparation method and application thereof | 合肥合源药业有限公司 | 2020-01-03 | — | — | CN | disclosed |