Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 5/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21644506 | 0.94 | POLB (0.51) | POLBAPEX1HTTTDP1RARB | |
| SCHEMBL21644498 | 0.91 | POLB (0.46) | POLBAPEX1HTTTDP1RARB | |
| SCHEMBL21644486 | 0.89 | POLB (0.45) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL7537131 | 0.86 | POLB (0.47) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL29723033 | 0.85 | POLB (0.49) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL25123439 | 0.84 | POLB (0.56) | POLBAPEX1HTTTDP1RARB | |
| SCHEMBL25796434 | 0.84 | POLB (0.56) | POLBAPEX1HTTTDP1RARB | |
| Methacrylic Acid SCHEMBL20496128 | 0.83 | THRB (0.44) | THRBKDM4ELMNAMEN1KMT2A | |
| SCHEMBL21644456 | 0.82 | POLB (0.39) | POLBAPEX1HTTTDP1RARB | |
| SCHEMBL27859695 | 0.82 | POLB (0.39) | POLBAPEX1HTTTDP1RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200041848-A1 | LIQUID CRYSTAL DEVICE AND METHOD OF MANUFACTURE THEREFOR | JSR CORPORATION (JP) | 2020-02-06 | — | — | US | disclosed |