Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MET | P08581 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30779650 | 1.00 | HSD17B10 (0.55) | HSD17B10ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL30779559 | 0.91 | HSD17B10 (0.57) | HSD17B10ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL21644575 | 0.91 | HSD17B10 (0.57) | HSD17B10ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL28412349 | 0.88 | HSD17B10 (0.55) | HSD17B10ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL21644610 | 0.86 | KDM1A (0.50) | ALDH1A1SMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL30779631 | 0.86 | KDM1A (0.50) | ALDH1A1SMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL21644606 | 0.86 | TSHR (0.53) | HSD17B10ALDH1A1SMN1; SMN2NPSR1POLB | |
| SCHEMBL30779553 | 0.86 | TSHR (0.53) | HSD17B10ALDH1A1SMN1; SMN2NPSR1POLB | |
| SCHEMBL28652995 | 0.86 | MEN1 (0.65) | HSD17B10ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL30575480 | 0.86 | MEN1 (0.65) | HSD17B10ALDH1A1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11479528-B2 | Heat shock protein 90 inhibitors | TAIPEI MEDICAL UNIVERSITY (TW) | 2022-10-25 | — | — | US | disclosed |
| US-20200039923-A1 | HEAT SHOCK PROTEIN 90 INHIBITORS | TAIPEI MEDICAL UNIVERSITY (TW) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039923-A1 | HEAT SHOCK PROTEIN 90 INHIBITORS | HSP90AB1, HSP90AB2P, HSP90AA1 | HSD17B10 1757/4885ALDH1A1 1138/4885SMN1; SMN2 4067/4885 |
| US-11479528-B2 | Heat shock protein 90 inhibitors | HSP90AB1, HSP90AB2P, HSP90AA1 | HSD17B10 1757/4885ALDH1A1 1138/4885SMN1; SMN2 4067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.