Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.51 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30575480 | 1.00 | MEN1 (0.65) | MEN1KMT2AALDH1A1MAPTSGMS2 | |
| SCHEMBL30575472 | 0.92 | KMT2A (0.55) | MEN1KMT2AALDH1A1MAPTSGMS2 | |
| SCHEMBL28638512 | 0.92 | KMT2A (0.55) | MEN1KMT2AALDH1A1MAPTSGMS2 | |
| SCHEMBL30575467 | 0.90 | LRRK2 (0.63) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28656558 | 0.90 | LRRK2 (0.63) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28412349 | 0.88 | HSD17B10 (0.55) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL21644598 | 0.86 | HSD17B10 (0.55) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL29077341 | 0.85 | SMN1; SMN2 (0.60) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL30575469 | 0.85 | CNR1 (0.58) | KMT2AALDH1A1GAASMN1; SMN2POLB | |
| SCHEMBL28662568 | 0.85 | CNR1 (0.58) | KMT2AALDH1A1GAASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812077-B | Benzamide compound, preparation method thereof, pharmaceutical composition and application | 中国科学院上海药物研究所 | 2023-08-22 | — | — | CN | disclosed |
| CN-112812077-A | Benzamide compound and preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2021-05-18 | — | — | CN | disclosed |