Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13762657 | 0.89 | CYP1A2 (0.53) | DGKACYP1A2EPHX2PAMTSHR | |
| SCHEMBL1519341 | 0.87 | CYP1A2 (0.52) | DGKACYP1A2EPHX2PAMTSHR | |
| SCHEMBL1402725 | 0.87 | CYP1A2 (0.52) | DGKACYP1A2EPHX2PAMTSHR | |
| SCHEMBL14900199 | 0.86 | CYP1A2 (0.55) | DGKACYP1A2TSHRLMNAMGAM | |
| SCHEMBL1403494 | 0.85 | CYP1A2 (0.50) | DGKACYP1A2EPHX2PAMTSHR | |
| SCHEMBL5014807 | 0.85 | CYP1A2 (0.53) | DGKACYP1A2TSHRLMNAMGAM | |
| SCHEMBL28200825 | 0.84 | HTR2C (0.57) | DGKAEPHX2PAMHTR2CTSHR | |
| Ethyl Tetradecanoate SCHEMBL31277626 | 0.83 | DGKA (0.62) | DGKACYP1A2PAMTSHRLMNA | |
| Sulfuric Acid SCHEMBL28124120 | 0.82 | DGKA (0.61) | DGKACYP1A2PAMTSHRLMNA | |
| SCHEMBL11907952 | 0.82 | CYP1A2 (0.48) | CYP1A2TSHRLMNAMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11534410-B2 | Amphotericin loaded PEGylated lipid nanoparticles and methods of use | UNIVERSITY OF MISSISSIPPI (US) | 2022-12-27 | — | — | US | disclosed |
| US-20210330598-A1 | Amphotericin Loaded Pegylated Lipid Nanoparticles And Methods Of Use | UNIVERSITY OF MISSISSIPPI | 2021-10-28 | — | — | US | disclosed |
| WO-2020028916-A1 | AMPHOTERICIN LOADED PEGYLATED LIPID NANOPARTICLES AND METHODS OF USE | UNIVERSITY OF MISSISSIPPI (US) | 2020-02-06 | — | — | WO | disclosed |