SCHEMBL21647129

SCHEMBL21647129

O=C(C=Cc1ccccc1O)c1ccc(Br)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.71
MAPK1 P28482 1/20 0.71
AR P10275 2/20 0.66
CYP1B1 Q16678 1/20 0.63
BCHE P06276 2/20 0.60
GUSB P08236 1/20 0.60
NFKB1 P19838 2/20 0.58
JUN P05412 1/20 0.58
NFE2L2 Q16236 1/20 0.58
ESR1 P03372 1/20 0.57
ESR2 Q92731 1/20 0.57
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA4 P22748 1/20 0.56
ALOX5 P09917 1/20 0.56
CHRNA7 P36544 4/20 0.55
LMNA P02545 1/20 0.54
TYR P14679 1/20 0.54
MEN1 O00255 1/20 0.54
HSP90AA1 P07900 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29837090 1.00 MAPT (0.71) MAPTMAPK1ARCYP1B1BCHE
SCHEMBL21647128 1.00 MAPT (0.71) MAPTMAPK1ARCYP1B1BCHE
SCHEMBL9250766 0.86 MAPT (0.76) MAPTMAPK1CYP1B1BCHEGUSB
SCHEMBL5576960 0.86 MAPT (0.76) MAPTMAPK1CYP1B1BCHEGUSB
SCHEMBL626787 0.86 MAPT (0.75) MAPTMAPK1CYP1B1BCHEGUSB
SCHEMBL626785 0.86 MAPT (0.75) MAPTMAPK1CYP1B1BCHEGUSB
SCHEMBL10893208 0.86 MAPT (0.75) MAPTMAPK1CYP1B1BCHEGUSB
SCHEMBL29420130 0.86 MAPT (0.75) MAPTMAPK1CYP1B1BCHEGUSB
Methane SCHEMBL728022 0.84 MAPT (0.73) MAPTMAPK1CYP1B1BCHEGUSB
SCHEMBL21647111 0.83 MAPT (1.00) MAPTMAPK1ARCYP1B1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108774207-B Cyclopenta [ c ] chromene compounds and process for preparing the same 苏州大学张家港工业技术研究院 2021-12-17 CN disclosed
WO-2020024099-A1 CYCLOPENTADIENYL [C] CHROMIUM COMPOUND AND PREPARATION METHOD THEREFOR 苏州大学张家港工业技术研究院 2020-02-06 WO disclosed