SCHEMBL21647263

SCHEMBL21647263

O=C(O)CC(CC(=O)O)(OOC(CC(=O)O)(CC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
CYP2C19 P33261 2/20 0.43
HIF1A Q16665 2/20 0.43
CYP2D6 P10635 1/20 0.43
TSHR P16473 1/20 0.43
HMGCR P04035 1/20 0.39
CHRM1 P11229 1/20 0.39
TBXA2R P21731 1/20 0.39
ADRA1A P35348 1/20 0.39
ACLY P53396 3/20 0.37
CPT2 P23786 2/20 0.36
KDM4E B2RXH2 1/20 0.33
FFAR1 O14842 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LDHA P00338 1/20 0.30
SRR Q9GZT4 1/20 0.30
LMNA P02545 1/20 0.30
ALKBH5 Q6P6C2 1/20 0.30
SUCNR1 Q9BXA5 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7516558 0.97 ALDH1A1 (0.43) ALDH1A1CYP2C19HIF1ACYP2D6TSHR
SCHEMBL28390182 0.97 ALDH1A1 (0.43) ALDH1A1CYP2C19HIF1ACYP2D6TSHR
SCHEMBL1414703 0.97 ALDH1A1 (0.43) ALDH1A1CYP2C19HIF1ACYP2D6TSHR
SCHEMBL28987886 0.85 ALDH1A1 (0.39) ALDH1A1CYP2C19HIF1ACYP2D6TSHR
SCHEMBL1641740 0.83 ALDH1A1 (0.42) ALDH1A1CYP2C19HIF1ACYP2D6TSHR
SCHEMBL9483954 0.82 ALDH1A1 (0.46) ALDH1A1CYP2C19HIF1ACYP2D6TSHR
SCHEMBL27415345 0.81 ALDH1A1 (0.40) ALDH1A1CYP2C19HIF1ACYP2D6TSHR
SCHEMBL5983979 0.81 CYP2C19 (0.39) ALDH1A1CYP2C19HIF1ACYP2D6TSHR
SCHEMBL14672664 0.81 ALDH1A1 (0.36) ALDH1A1CYP2C19HIF1ACYP2D6TSHR
SCHEMBL108616 0.80 ALDH1A1 (0.43) ALDH1A1CYP2C19HIF1ACYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3829311-A1 CITRATE PERHYDRATES AND USES THEREOF Compagnie Vranken (FR) 2021-06-09 EP disclosed
WO-2020025816-A1 CITRATE PERHYDRATES AND USES THEREOF COMPAGNIE POUR LE HAUT COMMERCE (FR) 2020-02-06 WO disclosed
CN-104684936-B Structural agent as liquid cleaner and personal care product 克宁克莱克合作侨兴公司 2017-10-17 CN disclosed