Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCPS | Q96C86 | 15/20 | 0.69 |
| ▸ | DHFR | P00374 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2166003 | 0.85 | DCPS (0.81) | DCPSDHFRCYP2D6 | |
| SCHEMBL2164637 | 0.84 | DCPS (0.75) | DCPSDHFRCYP2D6 | |
| SCHEMBL2166718 | 0.83 | DCPS (0.71) | DCPSDHFRCYP2D6 | |
| SCHEMBL2164721 | 0.83 | DCPS (0.74) | DCPSDHFRCYP2D6 | |
| SCHEMBL1155318 | 0.83 | DCPS (0.74) | DCPSDHFRCYP2D6 | |
| SCHEMBL2165373 | 0.83 | DCPS (0.72) | DCPSDHFRCYP2D6 | |
| SCHEMBL1154905 | 0.83 | DCPS (0.74) | DCPSDHFRCYP2D6 | |
| SCHEMBL2166197 | 0.83 | DCPS (0.71) | DCPSDHFRCYP2D6 | |
| SCHEMBL2165530 | 0.83 | DCPS (0.71) | DCPSDHFRCYP2D6 | |
| SCHEMBL2164648 | 0.82 | DCPS (0.70) | DCPSDHFRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985755-B2 | 2,4-diaminoquinazolines for spinal muscular atrophy | FAMILIES OF SPINAL MUSCULAR ATROPHY (US) | 2011-07-26 | — | — | US | claimed |