Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29592629 | 0.84 | EGFR (0.56) | KDM4EHSD17B10MEN1KMT2AHPGD | |
| SCHEMBL21437996 | 0.84 | EGFR (0.56) | KDM4EHSD17B10MEN1KMT2AHPGD | |
| SCHEMBL490901 | 0.84 | EGFR (0.56) | CYP4F2CYP4A11ALDH1A1GAAKDM4E | |
| SCHEMBL22566901 | 0.84 | CYP4F2 (0.50) | CYP4F2CYP4A11ALDH1A1GAAKDM4E | |
| SCHEMBL2691039 | 0.84 | CYP4F2 (0.50) | CYP4F2CYP4A11ALDH1A1GAAMEN1 | |
| SCHEMBL31248058 | 0.84 | CYP4F2 (0.50) | CYP4F2CYP4A11ALDH1A1GAAKDM4E | |
| SCHEMBL3906109 | 0.83 | CYP4F2 (0.53) | CYP4F2CYP4A11ALDH1A1GAAKDM4E | |
| SCHEMBL21465435 | 0.82 | TSHR (0.49) | CYP4F2CYP4A11ALDH1A1GAAKDM4E | |
| SCHEMBL27792899 | 0.82 | CYP4F2 (0.49) | CYP4F2CYP4A11ALDH1A1GAAKDM4E | |
| SCHEMBL490899 | 0.82 | CYP4F2 (0.54) | CYP4F2CYP4A11ALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250188023-A1 | BENZENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-06-12 | — | — | US | disclosed |
| US-12258308-B2 | Benzene derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-03-25 | — | — | US | disclosed |
| CN-112513011-B | Benzene derivatives | 小野药品工业株式会社 | 2023-06-16 | — | — | CN | disclosed |
| US-20220089532-A1 | BENZENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-03-24 | — | — | US | disclosed |
| US-11261154-B2 | Benzene derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-03-01 | — | — | US | disclosed |
| US-20210332009-A1 | BENZENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2021-10-28 | — | — | US | disclosed |
| EP-3831810-A1 | BENZENE DERIVATIVE | ONO Pharmaceutical Co., Ltd. (JP) | 2021-06-09 | — | — | EP | disclosed |
| CN-112513011-A | Benzene derivatives | 小野药品工业株式会社 | 2021-03-16 | — | — | CN | disclosed |
| WO-2020027150-A1 | BENZENE DERIVATIVE | 小野薬品工業株式会社 | 2020-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12258308-B2 | Benzene derivative | PMP22, TMBIM6, MYT1 | CYP4F2 2972/4885CYP4A11 2997/4885ALDH1A1 1189/4885 |
| US-11261154-B2 | Benzene derivative | PMP22, TMBIM6, MYT1 | CYP4F2 2972/4885CYP4A11 2997/4885ALDH1A1 1189/4885 |
| US-20250188023-A1 | BENZENE DERIVATIVE | PMP22, TMBIM6, MYT1 | CYP4F2 2953/4885CYP4A11 2903/4885ALDH1A1 1203/4885 |
| US-20210332009-A1 | BENZENE DERIVATIVE | PMP22, TMBIM6, MYT1 | CYP4F2 2972/4885CYP4A11 2997/4885ALDH1A1 1189/4885 |
| US-20220089532-A1 | BENZENE DERIVATIVE | PMP22, TMBIM6, MYT1 | CYP4F2 2972/4885CYP4A11 2997/4885ALDH1A1 1189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.