Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CTH | P32929 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21648125 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2EPHX2ALDH1A1CYP2C19NPC1 | |
| SCHEMBL21648128 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2EPHX2ALDH1A1CYP2C19NPC1 | |
| SCHEMBL21648207 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2EPHX2ALDH1A1CYP2C19NPC1 | |
| SCHEMBL12108477 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1CYP2C19KDM4EHSD17B10 | |
| SCHEMBL21648073 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP2C19HPGDNPC1RAB9A | |
| SCHEMBL21648083 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1CYP2C19CYP2D6HPGD | |
| SCHEMBL21648152 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2EPHX2ALDH1A1CYP2C19KMT2A | |
| SCHEMBL21648126 | 0.76 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL21648129 | 0.76 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL21648133 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP2C19KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200030215-A1 | AQUEOUS COMPOSITION COMPRISING A COMPOUND OF THIOLACTONE TYPE AND A SILICONE AND PROCESS FOR TREATING KERATIN MATERIALS WITH THE COMPOSITION | L'OREAL (FR) | 2020-01-30 | — | — | US | disclosed |
| US-20200031796-A1 | COMPOSITION COMPRISING A COMPOUND OF THIOLACTONE TYPE AND A PARTICULAR SOLVENT AND PROCESS FOR TREATING KERATIN MATERIALS WITH THE COMPOSITION | L'OREAL (FR) | 2020-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200030215-A1 | AQUEOUS COMPOSITION COMPRISING A COMPOUND OF THIOLACTONE TYPE AND A SILICONE AND PROCESS FOR TREATING KERATIN MATERIALS WITH THE COMPOSITION | KRT18, MUC1, MGMT | SMN1; SMN2 3610/4885EPHX2 3579/4885ALDH1A1 2831/4885 |
| US-20200031796-A1 | COMPOSITION COMPRISING A COMPOUND OF THIOLACTONE TYPE AND A PARTICULAR SOLVENT AND PROCESS FOR TREATING KERATIN MATERIALS WITH THE COMPOSITION | KRT18, KRTCAP2, MUC1 | SMN1; SMN2 4724/4885EPHX2 2738/4885ALDH1A1 3178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.