Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.35 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29692634 | 0.99 | SCN8A (0.39) | SCN8AHTR1ACHRM2MAP4K4CYP1A2 | |
| SCHEMBL21648402 | 0.86 | SCN8A (0.49) | SCN8AHTR1ACHRM2MAP4K4CYP1A2 | |
| Hydrochloric Acid SCHEMBL29885630 | 0.85 | SCN8A (0.48) | SCN8AHTR1ACHRM2MAP4K4CYP1A2 | |
| SCHEMBL16264585 | 0.84 | CHRM2 (0.45) | SCN8AHTR1ACHRM2MAP4K4CYP1A2 | |
| SCHEMBL24720378 | 0.84 | CYP1A2 (0.53) | SCN8ACHRM2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL21648307 | 0.84 | CYP1A2 (0.53) | SCN8ACHRM2CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL29778279 | 0.83 | CHRM2 (0.44) | SCN8AHTR1ACHRM2MAP4K4CYP1A2 | |
| Hydrochloric Acid SCHEMBL29885598 | 0.83 | CYP1A2 (0.55) | SCN8ACHRM2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL16264651 | 0.81 | CHRM2 (0.53) | SCN8ACHRM2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL21648277 | 0.80 | HRH4 (0.49) | HTR1ACHRM2CYP1A2CYP2D6CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3606344-B1 | COMPOSITIONS AND METHODS COMPRISING A TRIARYL POLYAMINE | CURZA GLOBAL LLC (US) | 2022-08-17 | — | — | EP | disclosed |
| US-11352315-B2 | Compositions and methods comprising a triaryl polyamine | CURZA GLOBAL, LLC (US) | 2022-06-07 | — | — | US | disclosed |
| US-20200031757-A1 | COMPOSITIONS AND METHODS COMPRISING A TRIARYL POLYAMINE | CURZA GLOBAL, LLC (US) | 2020-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352315-B2 | Compositions and methods comprising a triaryl polyamine | SRM, PARG, PARN | SCN8A 4868/4885HTR1A 3092/4885CHRM2 4059/4885 |
| US-20200031757-A1 | COMPOSITIONS AND METHODS COMPRISING A TRIARYL POLYAMINE | SRM, PARG, PARN | SCN8A 4868/4885HTR1A 3092/4885CHRM2 4059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.