Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5782185 | 0.88 | HSD17B10 (0.44) | HSD17B10SMN1; SMN2HSD11B1NPC1LMNA | |
| SCHEMBL5782181 | 0.88 | HSD17B10 (0.44) | HSD17B10SMN1; SMN2HSD11B1NPC1LMNA | |
| SCHEMBL9003564 | 0.87 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2HSD11B1NPC1LMNA | |
| SCHEMBL30396554 | 0.87 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2HSD11B1NPC1LMNA | |
| SCHEMBL15029642 | 0.85 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2HSD11B1RAB9ANPC1 | |
| SCHEMBL73360 | 0.82 | HSD17B10 (0.56) | HSD17B10SMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL73359 | 0.82 | HSD17B10 (0.56) | HSD17B10SMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL1631708 | 0.82 | HSD17B10 (0.56) | HSD17B10SMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL6219872 | 0.80 | HSD17B10 (0.69) | HSD17B10SMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL85536 | 0.80 | HSD17B10 (0.69) | HSD17B10SMN1; SMN2RAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023073-A1 | ALLOSTERIC MODULATORS OF THE MU OPIOID RECEPTOR | Chiromics, LLC (US) | 2020-01-30 | — | — | WO | disclosed |