Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9003564 | 1.00 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2HSD11B1EPHX2NPC1 | |
| SCHEMBL21649014 | 0.87 | HSD17B10 (0.48) | HSD17B10SMN1; SMN2HSD11B1NPC1LMNA | |
| SCHEMBL8255174 | 0.85 | NR1H2 (0.42) | HSD17B10SMN1; SMN2HSD11B1EPHX2NPC1 | |
| SCHEMBL934024 | 0.85 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2HSD11B1EPHX2NPC1 | |
| SCHEMBL14488388 | 0.85 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2HSD11B1EPHX2NPC1 | |
| SCHEMBL16824583 | 0.85 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2HSD11B1EPHX2NPC1 | |
| SCHEMBL2905429 | 0.84 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2EPHX2USP2 | |
| SCHEMBL2905427 | 0.84 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2EPHX2USP2 | |
| SCHEMBL16584822 | 0.84 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2EPHX2USP2 | |
| SCHEMBL2126924 | 0.84 | HSD17B10 (0.45) | HSD17B10SMN1; SMN2HSD11B1EPHX2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096714-A | Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections | 安力高医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-4165037-A1 | ANTI-VIRAL COMPOUNDS FOR TREATING CORONAVIRUS, PICORNAVIRUS, AND NOROVIRUS INFECTIONS | Aligos Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |