Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.82 |
| ▸ | TLR8 | Q9NR97 | 14/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13976699 | 0.92 | TLR7 (0.83) | TLR7TLR8 | |
| SCHEMBL24757414 | 0.91 | TLR7 (0.95) | TLR7TLR8 | |
| SCHEMBL21632437 | 0.91 | TLR7 (0.88) | TLR7TLR8 | |
| SCHEMBL20766799 | 0.90 | TLR7 (0.96) | TLR7TLR8 | |
| SCHEMBL29381770 | 0.90 | TLR7 (0.96) | TLR7TLR8 | |
| SCHEMBL19299789 | 0.90 | TLR7 (0.86) | TLR7TLR8 | |
| SCHEMBL22522321 | 0.90 | TLR7 (0.80) | TLR7TLR8 | |
| SCHEMBL16021125 | 0.90 | TLR7 (0.86) | TLR7TLR8 | |
| SCHEMBL13968059 | 0.90 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL16019254 | 0.89 | TLR7 (1.00) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023680-A1 | TLR7/8 AGONISTS AND LIPOSOME COMPOSITIONS | TORQUE THERAPEUTICS, INC. (US) | 2020-01-30 | — | — | WO | disclosed |