Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.88 |
| ▸ | TLR8 | Q9NR97 | 13/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24757414 | 0.94 | TLR7 (0.95) | TLR7TLR8 | |
| SCHEMBL20766799 | 0.94 | TLR7 (0.96) | TLR7TLR8 | |
| SCHEMBL29381770 | 0.94 | TLR7 (0.96) | TLR7TLR8 | |
| SCHEMBL13968059 | 0.94 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL16021125 | 0.94 | TLR7 (0.86) | TLR7TLR8 | |
| SCHEMBL19299789 | 0.94 | TLR7 (0.86) | TLR7TLR8 | |
| SCHEMBL20983639 | 0.93 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL29382380 | 0.93 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL16019253 | 0.93 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL16019254 | 0.93 | TLR7 (1.00) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210393523-A1 | AROMATIC RING SUBSTITUTED AMPHIPHILIC POLYMERS AS DRUG DELIVERY SYSTEMS | Avldea Technologies, Inc. (US) | 2021-12-23 | — | — | US | disclosed |
| US-20210213010-A1 | TLR7/8 AGONISTS AND LIPOSOME COMPOSITIONS | DANMARKS TEKNISKE UNIVERSITET (DK) | 2021-07-15 | — | — | US | disclosed |
| US-20210213010-A1 | TLR7/8 AGONISTS AND LIPOSOME COMPOSITIONS | DANMARKS TEKNISKE UNIVERSITET (DK) | 2021-07-15 | — | — | US | disclosed |
| EP-3827002-A1 | TLR7/8 AGONISTS AND LIPOSOME COMPOSITIONS | Torque Therapeutics, Inc. (US) | 2021-06-02 | — | — | EP | disclosed |
| WO-2020023680-A1 | TLR7/8 AGONISTS AND LIPOSOME COMPOSITIONS | TORQUE THERAPEUTICS, INC. (US) | 2020-01-30 | — | — | WO | disclosed |
| WO-2020023680-A1 | TLR7/8 AGONISTS AND LIPOSOME COMPOSITIONS | TORQUE THERAPEUTICS, INC. (US) | 2020-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210213010-A1 | TLR7/8 AGONISTS AND LIPOSOME COMPOSITIONS | TLR7, TLR9, TLR8 | TLR7 1/4885TLR8 3/4885 |
| US-20210393523-A1 | AROMATIC RING SUBSTITUTED AMPHIPHILIC POLYMERS AS DRUG DELIVERY SYSTEMS | SBDS, APOB, ABCD3 | TLR7 956/4885TLR8 1007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.