Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23436757 | 0.87 | BRD4 (0.63) | BRD4 | |
| SCHEMBL21652831 | 0.84 | BRD4 (0.68) | BRD4 | |
| SCHEMBL21652824 | 0.84 | BRD4 (0.64) | BRD4 | |
| SCHEMBL15069293 | 0.83 | BRD4 (0.76) | BRD4 | |
| SCHEMBL23436641 | 0.82 | BRD4 (0.76) | BRD4 | |
| SCHEMBL31073856 | 0.81 | BRD4 (0.72) | BRD4 | |
| SCHEMBL23436760 | 0.80 | BRD4 (0.77) | BRD4 | |
| SCHEMBL21652740 | 0.80 | BRD4 (0.77) | BRD4 | |
| SCHEMBL29745710 | 0.80 | BRD4 (1.00) | BRD4 | |
| SCHEMBL15069284 | 0.80 | BRD4 (1.00) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021143922-A1 | CRYSTAL FORM AND SALT FORM OF BROMINE DOMAIN PROTEIN INHIBITOR AND PREPARATION METHOD THEREFOR | 正大天晴药业集团股份有限公司 | 2021-07-22 | — | — | WO | disclosed |
| EP-3828183-A1 | SULFOXIMINE COMPOUND AS BROMODOMAIN PROTEIN INHIBITOR AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2021-06-02 | — | — | EP | disclosed |
| WO-2020020288-A1 | SULFOXIMINE COMPOUND AS BROMODOMAIN PROTEIN INHIBITOR AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 正大天晴药业集团股份有限公司 | 2020-01-30 | — | — | WO | disclosed |