Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.74 |
| ▸ | BRD2 | P25440 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.62 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21652807 | 0.91 | BRD4 (0.65) | BRD4BRD2KCNH2BRD3BRDT | |
| SCHEMBL23437463 | 0.90 | BRD4 (0.64) | BRD4BRD2KCNH2BRD3BRDT | |
| SCHEMBL21652758 | 0.89 | BRD4 (0.62) | BRD4BRD2KCNH2BRD3BRDT | |
| SCHEMBL25249935 | 0.88 | BRD4 (0.80) | BRD4BRD2KCNH2BRD3BRDT | |
| SCHEMBL24630351 | 0.88 | BRD4 (0.70) | BRD4BRD2KCNH2BRD3BRDT | |
| SCHEMBL30498808 | 0.88 | BRD4 (0.80) | BRD4BRD2KCNH2BRD3BRDT | |
| SCHEMBL25809353 | 0.88 | BRD4 (0.81) | BRD4BRD2KCNH2BRD3BRDT | |
| SCHEMBL21652836 | 0.86 | BRD4 (0.61) | BRD4BRD2KCNH2BRD3BRDT | |
| SCHEMBL15067734 | 0.85 | BRD4 (1.00) | BRD4 | |
| SCHEMBL29745691 | 0.85 | BRD4 (1.00) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020020288-A1 | SULFOXIMINE COMPOUND AS BROMODOMAIN PROTEIN INHIBITOR AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 正大天晴药业集团股份有限公司 | 2020-01-30 | — | — | WO | disclosed |