Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 12/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 8/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20458052 | 0.98 | ESR1 (0.42) | ESR1ESR2CNR2MEN1KMT2A | |
| SCHEMBL19592942 | 0.82 | SMN1; SMN2 (0.41) | ESR1ESR2CNR2MEN1KMT2A | |
| SCHEMBL21695082 | 0.82 | CNR2 (0.39) | ESR1ESR2CNR2LMNASMN1; SMN2 | |
| SCHEMBL20097921 | 0.81 | CNR2 (0.42) | ESR1ESR2CNR2CNR1 | |
| SCHEMBL22024340 | 0.81 | MEN1 (0.41) | ESR1ESR2MEN1KMT2ALMNA | |
| SCHEMBL18494777 | 0.81 | CNR2 (0.58) | CNR2CNR1 | |
| SCHEMBL22955761 | 0.81 | ESR1 (0.46) | ESR1ESR2MEN1KMT2ALMNA | |
| SCHEMBL21549391 | 0.80 | HDAC3 (0.45) | ESR1ESR2CNR2LMNACNR1 | |
| SCHEMBL21185893 | 0.80 | ESR1 (0.39) | ESR1ESR2CNR2LMNASMN1; SMN2 | |
| SCHEMBL25622565 | 0.80 | CNR2 (0.35) | ESR1ESR2CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10993938-B2 | Lactam compound, preparation method and use thereof | OCEAN UNIVERSITY OF CHINA (CN) | 2021-05-04 | — | — | US | disclosed |
| US-20200030312-A1 | Lactam Compound, Preparation Method and Use thereof | OCEAN UNIVERSITY OF CHINA (CN) | 2020-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200030312-A1 | Lactam Compound, Preparation Method and Use thereof | FURIN, PEPD, PIN1 | ESR1 4118/4885ESR2 4702/4885CNR2 3955/4885 |
| US-10993938-B2 | Lactam compound, preparation method and use thereof | FURIN, PEPD, PIN1 | ESR1 4118/4885ESR2 4702/4885CNR2 3955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.