Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.51 |
| ▸ | MAP4K1 | Q92918 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17442710 | 0.82 | KLKB1 (0.74) | KLKB1MAP4K1 | |
| SCHEMBL18369394 | 0.72 | KLKB1 (0.69) | KLKB1MAP4K1 | |
| SCHEMBL17447302 | 0.69 | KLKB1 (0.67) | KLKB1MAP4K1 | |
| SCHEMBL16881340 | 0.69 | KLKB1 (0.82) | KLKB1MAP4K1 | |
| SCHEMBL19354895 | 0.68 | KLKB1 (0.48) | KLKB1MAP4K1 | |
| SCHEMBL18458835 | 0.67 | KLKB1 (0.58) | KLKB1MAP4K1 | |
| SCHEMBL17442787 | 0.67 | KLKB1 (1.00) | KLKB1MAP4K1 | |
| SCHEMBL18369559 | 0.66 | KLKB1 (1.00) | KLKB1MAP4K1 | |
| SCHEMBL23279825 | 0.66 | KLKB1 (0.69) | KLKB1MAP4K1 | |
| SCHEMBL23269751 | 0.66 | KLKB1 (0.56) | KLKB1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200031799-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | ATTUNE PHARMACEUTICALS, INC. | 2020-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200031799-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | KLKB1, SERPINB1, SERPINE1 | KLKB1 1/4885MAP4K1 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.