SCHEMBL21657352

SCHEMBL21657352

CN1C(=O)OCC1C(Cl)Cl

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.42
IL6ST P40189 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21657351 0.84 PIK3CD (0.40) PIK3CDIL6ST
SCHEMBL2033251 0.83 PIK3CD (0.42) PIK3CDIL6ST
SCHEMBL10570167 0.81 PIK3CD (0.41) PIK3CDIL6ST
SCHEMBL9926814 0.81 PIK3CD (0.56) PIK3CDIL6ST
SCHEMBL9926817 0.81 PIK3CD (0.56) PIK3CDIL6ST
SCHEMBL10049353 0.81 PIK3CD (0.56) PIK3CDIL6ST
SCHEMBL10308941 0.75 PIK3CD (0.42) PIK3CDIL6ST
SCHEMBL21657357 0.71
SCHEMBL23016742 0.69 PIK3CD (0.34) PIK3CD
SCHEMBL12240415 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020020385-A1 TRICYCLIC DERIVATIVE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION 上海翰森生物医药科技有限公司 2020-01-30 WO disclosed