Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.56 |
| ▸ | IL6ST | P40189 | 5/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 13/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10049353 | 1.00 | PIK3CD (0.56) | PIK3CDIL6STARSTAT3IDH1 | |
| SCHEMBL9926814 | 1.00 | PIK3CD (0.56) | PIK3CDIL6STARSTAT3IDH1 | |
| SCHEMBL21657352 | 0.81 | PIK3CD (0.42) | PIK3CDIL6ST | |
| SCHEMBL2033251 | 0.81 | PIK3CD (0.42) | PIK3CDIL6ST | |
| SCHEMBL10308941 | 0.80 | PIK3CD (0.42) | PIK3CDIL6STIDH1 | |
| SCHEMBL1717114 | 0.79 | PIK3CD (0.44) | PIK3CDIL6STARSTAT3IDH1 | |
| SCHEMBL12706216 | 0.79 | PIK3CD (0.41) | PIK3CDIL6ST | |
| SCHEMBL21657351 | 0.78 | PIK3CD (0.40) | PIK3CDIL6ST | |
| SCHEMBL10308833 | 0.77 | PIK3CD (0.55) | PIK3CDIL6STSTAT3IDH1 | |
| SCHEMBL18391318 | 0.77 | PIK3CD (0.55) | PIK3CDIL6STSTAT3IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464297-B1 | PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF | Dr Reddys Laboratories Ltd (IN) | 2023-10-25 | — | — | EP | disclosed |
| US-10836776-B2 | Process for preparation of eribulin and intermediates thereof | DR. REDDY'S LABORATORIES LIMITED (IN) | 2020-11-17 | — | — | US | disclosed |
| US-20190276470-A1 | PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF | DR. REDDY'S LABORATORIES LIMITED (IN) | 2019-09-12 | — | — | US | disclosed |
| WO-2017203459-A1 | PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF | DR. REDDY'S LABORATORIES LIMITED (IN) | 2017-11-30 | — | — | WO | disclosed |
| US-20170204065-A1 | PROCESS FOR THE PREPARATION OF KINASE INHIBITORS AND INTERMEDIATES THEREOF | ALCON INC. (CH) | 2017-07-20 | — | — | US | disclosed |
| US-20170137384-A1 | PROCESS FOR THE PREPARATION OF KINASE INHIBITORS AND INTERMEDIATES THEREOF | ALCON INC. (CH) | 2017-05-18 | — | — | US | disclosed |
| US-9624183-B2 | Process for the preparation of a fluorolacton derivative | GILEAD PHARMASSET LLC (US) | 2017-04-18 | — | — | US | disclosed |
| US-20150315165-A1 | PROCESS FOR THE PREPARATION OF A FLUOROLACTON DERIVATIVE | HOFFMANN-LA ROCHE INC. (US) | 2015-11-05 | — | — | US | disclosed |
| US-8703963-B2 | Derivative N-thiolated 2-oxazolidinone antibiotics | UNIVERSITY OF SOUTH FLORIDA (US) | 2014-04-22 | — | — | US | disclosed |
| WO-2013151161-A1 | NOVEL COMPOUND, METHOD FOR PRODUCING SAME AND ANTITUMOR AGENT | 学校法人東京理科大学 (JP) | 2013-10-10 | — | — | WO | disclosed |
| US-8354401-B2 | Oxazolidinone amide aromatic compounds for supressing MMP-9 production | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-01-15 | — | — | US | disclosed |
| US-20120149911-A1 | DERIVATIVE N-THIOLATED 2-OXAZOLIDINONE ANTIBIOTICS | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-06-14 | — | — | US | disclosed |
| US-20110263571-A1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-10-27 | — | — | US | disclosed |
| US-8017779-B2 | Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-09-13 | — | — | US | disclosed |
| US-8017779-B2 | Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-09-13 | — | — | US | disclosed |
| US-20070213356-A1 | Nitrogen-Containing Heterocyclyl Substituted Imidazoquinolines and Imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY | 2007-09-13 | — | — | US | disclosed |
| US-20070213356-A1 | Nitrogen-Containing Heterocyclyl Substituted Imidazoquinolines and Imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10836776-B2 | Process for preparation of eribulin and intermediates thereof | ERLIN1, ERLIN2, DHPS | PIK3CD 1977/4885IL6ST 2497/4885AR 2217/4885 |
| US-20170137384-A1 | PROCESS FOR THE PREPARATION OF KINASE INHIBITORS AND INTERMEDIATES THEREOF | MAP3K1, MAP3K6, MAP3K7 | PIK3CD 103/4885IL6ST 3302/4885AR 4536/4885 |
| US-20070213356-A1 | Nitrogen-Containing Heterocyclyl Substituted Imidazoquinolines and Imidazonaphthyridines | IL2, IFNG, IRF3 | PIK3CD 1555/4885IL6ST 24/4885AR 4158/4885 |
| US-20120149911-A1 | DERIVATIVE N-THIOLATED 2-OXAZOLIDINONE ANTIBIOTICS | TST, NRDC, NUCB2 | PIK3CD 4556/4885IL6ST 3917/4885AR 2906/4885 |
| US-20170204065-A1 | PROCESS FOR THE PREPARATION OF KINASE INHIBITORS AND INTERMEDIATES THEREOF | MAP3K1, MAP3K6, MAP3K7 | PIK3CD 103/4885IL6ST 3302/4885AR 4536/4885 |
| US-20150315165-A1 | PROCESS FOR THE PREPARATION OF A FLUOROLACTON DERIVATIVE | CYP2B6, CYP2F1, CYP3A5 | PIK3CD 3266/4885IL6ST 508/4885AR 2940/4885 |
| US-20110263571-A1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | MMP9, MMP10, MMP2 | PIK3CD 4654/4885IL6ST 554/4885AR 2260/4885 |
| US-20190276470-A1 | PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF | ERLIN1, ERLIN2, DHPS | PIK3CD 1977/4885IL6ST 2497/4885AR 2217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.