Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15427129 | 0.88 | KCNA3 (0.47) | KCNA3TTRKDM4ETP53MAPK1 | |
| SCHEMBL15427134 | 0.86 | ELANE (0.54) | KCNA3TTRELANE | |
| SCHEMBL15427118 | 0.86 | TTR (0.55) | KCNA3TTRKDM4ETP53MAPK1 | |
| SCHEMBL15427085 | 0.84 | KCNA3 (0.47) | KCNA3TTRTP53ELANEMAPT | |
| SCHEMBL30760689 | 0.84 | SLC37A4 (0.51) | KCNA3TTRKDM4ETP53MAPK1 | |
| SCHEMBL30760699 | 0.83 | KCNA3 (0.46) | KCNA3TTRKDM4ETP53MAPK1 | |
| SCHEMBL30760690 | 0.82 | KCNA3 (0.45) | KCNA3TTRKDM4ETP53MAPK1 | |
| SCHEMBL30760709 | 0.82 | KCNA3 (0.48) | KCNA3TTRKDM4ETP53MAPK1 | |
| SCHEMBL15427191 | 0.82 | KCNA3 (0.42) | KCNA3TTRKDM4ETP53MAPK1 | |
| SCHEMBL16919801 | 0.81 | KCNA3 (0.46) | KCNA3TTRMAPK1ELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544090-B2 | Anthraquinone analogs and methods of making and using thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2020-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544090-B2 | Anthraquinone analogs and methods of making and using thereof | PCNA, KRAS, RECQL | KCNA3 3827/4885TTR 4284/4885KDM4E 1197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.