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Sugi Predict / Targets / SLC37A4

SLC37A4

Glucose-6-phosphate exchanger SLC37A4 · O43826 · SLC37A4 on Sugi Atlas →

1,572 patent compounds predicted against SLC37A4, 866 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL16225767 SCHEMBL16225767 1.00 8/20
SCHEMBL16225770 SCHEMBL16225770 1.00 8/20
SCHEMBL16226660 SCHEMBL16226660 1.00 8/20
SCHEMBL16226662 SCHEMBL16226662 1.00 8/20
Mumbaistatin Mumbaistatin (SCHEMBL13238512) 1.00 7/20
SCHEMBL16431884 SCHEMBL16431884 0.86 7/20
Anthraquinone Anthraquinone (SCHEMBL3670422) 0.83 7/20
SCHEMBL5142787 SCHEMBL5142787 0.67 7/20
SCHEMBL16226021 SCHEMBL16226021 0.61 7/20
SCHEMBL13317458 SCHEMBL13317458 0.58 7/20
SCHEMBL16226654 SCHEMBL16226654 0.56 7/20
SCHEMBL16227276 SCHEMBL16227276 0.53 7/20
SCHEMBL10968010 SCHEMBL10968010 0.47 7/20
SCHEMBL15827616 SCHEMBL15827616 0.87 6/20
SCHEMBL3670424 SCHEMBL3670424 0.60 6/20
SCHEMBL23199041 SCHEMBL23199041 0.56 6/20
SCHEMBL23198954 SCHEMBL23198954 0.53 6/20
Knipholone Knipholone (SCHEMBL16226780) 0.47 6/20
SCHEMBL16226885 SCHEMBL16226885 0.46 6/20
SCHEMBL21067467 SCHEMBL21067467 0.45 6/20

Clinical trials — most relevant to SLC37A4 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effect of Age on the Renal Clearance of Adefovir PHASE4WITHDRAWN
Study of the Anti-FGF23 Antibody, Burosumab, in Adults With XLH PHASE3COMPLETED
Applying Proton Pump Inhibitor to Prevent and Treat Acute Fluctuating Hearing Loss in Patients With SLC26A4 Mutation PHASE2/PHASE3UNKNOWN
Safety, Efficacy Evaluation of Empagliflozin Administration for Neutropenia in Glycogenosis Type 1b and G6PC3 Deficiency PHASE2UNKNOWN
CHED - Congenital Hereditary Endothelial Dystrophy: New Paradigm Shift in Therapy Using Topical Eye Drops PHASE2UNKNOWN
Intrathecal Gene Therapy For SLC13A5 Citrate Transporter Disorder PHASE1/PHASE2NOT_YET_RECRUITING
Effect of, OAT3, on the Renal Secretion of Cefotaxime PHASE1COMPLETED
Tolerability of Enteral NAC in Infants PHASE1NOT_YET_RECRUITING
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy nanCOMPLETED
Biomarker for Glycogen Storage Diseases (BioGlycogen) nanWITHDRAWN
SLC13A5 Deficiency Natural History Study - Remote Only nanENROLLING_BY_INVITATION
Clinical and Genetic Analysis of Enlarged Vestibular Aqueducts nanCOMPLETED
Identification and Characterization of Monogenic Diabetes nanCOMPLETED
Bile Acid Effects in Fetal Arrhythmia Study nanUNKNOWN
Gyrate Atrophy Ocular and Systemic Study nanACTIVE_NOT_RECRUITING
Genetic Variants and Iron Absorption nanCOMPLETED
Oxalate and Citrate in Humans - Response to Citrate nanRECRUITING
Baseline Physiology Studies in Carriers of Gene Variant X Conferring Major Risk of CVD-prone Metabolic Disorders nanCOMPLETED
Candidate Gene for Hyperferritinemia nanUNKNOWN
Prevalence and Risk Factors of Nephrocalcinosis in Children at Sohag University Hospital nanUNKNOWN
SLC13A5 Deficiency Natural History Study - United States Only nanENROLLING_BY_INVITATION
Epidemiology of Gout in French Polynesia nanCOMPLETED
Genetic and Biohumoral Factors Involved in Menière's Disease and Their Correlation With Phenotypes nanRECRUITING
Genetic Study for Infantile Onset Diabetes Mellitus nanUNKNOWN
Individualized Antiretroviral Therapy nanCOMPLETED
Gastrostomy-Biliary Diversion: Innovative Management for Bile Canalicular Transport Disorders nanUNKNOWN
Characterization of Dysmorphology in Subjects With Creatine Transporter Deficiency nanRECRUITING
Genotype-phenotype Correlation of SLC26A4 in CI Patients With EVA nanUNKNOWN
Phenotypic and Genotypic Studies in Congenital and Early Onset Ataxias nanCOMPLETED
The Natural History of TRPV4 Neuropathy nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a SLC37A4 binder may also engage these)

ProteinNameSimilarity
Q2QWW7 — 0.961 Q2QWW7 →
Q53P54 — 0.961 Q53P54 →
Q640L2 — 0.961 Q640L2 →
Q9FLG8 — 0.960 Q9FLG8 →
Q9FKV1 — 0.958 Q9FKV1 →
Q6NMN6 — 0.956 Q6NMN6 →
Q53WP9 — 0.956 Q53WP9 →
Q4LE88 — 0.955 Q4LE88 →
P27669 — 0.954 P27669 →
Q7XJR2 — 0.953 Q7XJR2 →
P30638 — 0.953 P30638 →
Q8W0H5 — 0.953 Q8W0H5 →
F4IKF6 — 0.952 F4IKF6 →
Q9UMX9 — 0.952 Q9UMX9 →
Q9LKH3 — 0.951 Q9LKH3 →
Q7L1I2 — 0.950 Q7L1I2 →
Q66GI9 — 0.950 Q66GI9 →
Q39231 — 0.950 Q39231 →
Q9C8X2 — 0.950 Q9C8X2 →
Q5F3N0 — 0.950 Q5F3N0 →
Q9ZVK6 — 0.949 Q9ZVK6 →
Q10R54 — 0.949 Q10R54 →
P58355 — 0.949 P58355 →
Q9C5L3 — 0.948 Q9C5L3 →
Q39232 — 0.948 Q39232 →
Q63564 — 0.948 Q63564 →
Q1LVS8 — 0.948 Q1LVS8 →
Q948L0 — 0.947 Q948L0 →
Q8TF71 — 0.947 Q8TF71 →
Q91Y77 — 0.947 Q91Y77 →