Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17251633 | 0.93 | TDP1 (0.49) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL21440854 | 0.81 | TDP1 (0.58) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL21440761 | 0.81 | TDP1 (0.53) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL9658266 | 0.80 | TDP1 (0.66) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL21440858 | 0.80 | TDP1 (0.56) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL24503567 | 0.76 | ALDH1A1 (0.55) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL9627050 | 0.75 | TDP1 (0.58) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| Benzyl Benzoate SCHEMBL252181 | 0.74 | TDP1 (0.85) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL31500283 | 0.73 | TDP1 (0.51) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL17969774 | 0.73 | ALDH1A1 (0.56) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143154-B1 | CHEMICALLY-LOCKED BISPECIFIC ANTIBODIES | SORRENTO THERAPEUTICS INC (US) | 2020-01-29 | — | — | EP | disclosed |