SCHEMBL21660583

SCHEMBL21660583

CCC(C)c1ccc(N(c2ccccc2)c2ccc(N)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.62
CYP3A4 P08684 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
CYP2C9 P11712 2/20 0.62
KDM4E B2RXH2 1/20 0.62
CYP1A2 P05177 1/20 0.62
CYP2D6 P10635 1/20 0.62
MAPT P10636 1/20 0.62
CYP2C19 P33261 1/20 0.62
TAAR1 Q96RJ0 2/20 0.41
TSHR P16473 2/20 0.41
PSMD14 O00487 1/20 0.41
MAPK1 P28482 1/20 0.41
RECQL P46063 1/20 0.41
GFER P55789 1/20 0.41
USP2 O75604 1/20 0.41
GAA P10253 1/20 0.41
PKM P14618 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19413370 0.91 ALDH1A1 (0.45) ALDH1A1CYP3A4TDP1L3MBTL1CYP2C9
SCHEMBL12012665 0.91 ALDH1A1 (0.45) ALDH1A1CYP3A4TDP1L3MBTL1CYP2C9
SCHEMBL2300944 0.91 ALDH1A1 (0.45) ALDH1A1CYP3A4TDP1L3MBTL1CYP2C9
SCHEMBL14523554 0.91 ALDH1A1 (0.45) ALDH1A1CYP3A4TDP1L3MBTL1CYP2C9
SCHEMBL11910659 0.89 ALDH1A1 (0.45) ALDH1A1CYP3A4TDP1L3MBTL1CYP2C9
SCHEMBL8673666 0.88 GRIA4 (0.46) ALDH1A1CYP3A4TDP1L3MBTL1CYP2C9
SCHEMBL12299146 0.86 GRIA4 (0.41) ALDH1A1CYP3A4TDP1L3MBTL1CYP2C9
SCHEMBL8531958 0.86 GRIA4 (0.41) ALDH1A1CYP3A4TDP1L3MBTL1CYP2C9
SCHEMBL18532935 0.85 ALDH1A1 (0.41) ALDH1A1CYP3A4TDP1L3MBTL1CYP2C9
SCHEMBL15458072 0.84 CYP2C19 (0.42) ALDH1A1CYP3A4TDP1L3MBTL1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020027014-A1 POLYMER AND USE OF SAME 日産化学株式会社 2020-02-06 WO disclosed