Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22479922 | 0.82 | — | — | |
| SCHEMBL25475096 | 0.72 | — | — | |
| SCHEMBL21447622 | 0.68 | FKBP5 (0.30) | CRBN | |
| SCHEMBL13068886 | 0.67 | GSK3A (0.38) | — | |
| SCHEMBL21349639 | 0.66 | MEN1 (0.31) | — | |
| SCHEMBL22694645 | 0.65 | — | — | |
| SCHEMBL21447620 | 0.64 | HTR2C (0.32) | — | |
| SCHEMBL22642201 | 0.64 | — | — | |
| SCHEMBL23889389 | 0.63 | GSK3B (0.31) | — | |
| SCHEMBL23395009 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023101710-A1 | METHODS OF TREATING BREAST CANCERS WITH SELECTIVE ANDROGEN RECEPTOR MODULATORS AND ADDITIONAL THERAPEUTIC AGENTS | VERU INC. (US) | 2023-06-08 | — | — | WO | disclosed |
| WO-2020028593-A9 | A METHOD OF TREATING ER MUTANT EXPRESSING BREAST CANCERS WITH SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | Oncternal Therapeutics, Inc. (US) | 2021-03-18 | — | — | WO | disclosed |
| EP-3733170-A1 | A METHOD OF TREATING ANDROGEN RECEPTOR (AR) -POSITIVE BREAST CANCERS WITH SELECTIVE ANDROGEN RECEPTOR MODULATOR (SARMS) | Oncternal Therapeutics, Inc. (US) | 2020-11-04 | — | — | EP | disclosed |
| WO-2020028593-A1 | A METHOD OF TREATING ER MUTANT EXPRESSING BREAST CANCERS WITH SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | Oncternal Therapeutics, Inc. (US) | 2020-02-06 | — | — | WO | disclosed |