Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PDE6D | O43924 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21660624 | 0.86 | MAPK1 (0.51) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL15446467 | 0.80 | ESR1 (0.56) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL14803183 | 0.78 | ESR1 (0.54) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL15446431 | 0.77 | ESR1 (0.50) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL23169740 | 0.77 | ESR1 (0.60) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL21660639 | 0.77 | HSD17B10 (0.43) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL26344964 | 0.77 | ESR2 (0.52) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL23169644 | 0.76 | ESR1 (0.58) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL15446587 | 0.76 | ESR1 (0.58) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL19271635 | 0.76 | L3MBTL1 (0.40) | KDM4EALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3583104-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-06-09 | — | — | EP | disclosed |
| US-10923665-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2021-02-16 | — | — | US | disclosed |
| US-20200044162-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10923665-B2 | Materials for organic electroluminescent devices | OR10J3, L1CAM, EPCAM | ESR1 78/4885ESR2 244/4885KDM4E 1917/4885 |
| US-20200044162-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | OR10J3, L1CAM, EPCAM | ESR1 78/4885ESR2 244/4885KDM4E 1917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.