Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29843816 | 0.88 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDMAPTNPSR1 | |
| SCHEMBL18921802 | 0.88 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDMAPTNPSR1 | |
| SCHEMBL20175787 | 0.87 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL19439415 | 0.86 | CYP1A1 (0.37) | ALDH1A1KDM4EHPGDMAPTNPSR1 | |
| SCHEMBL24891224 | 0.85 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDMAPTNPSR1 | |
| SCHEMBL15791097 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDMAPTNPSR1 | |
| SCHEMBL16785752 | 0.85 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDMAPTNPSR1 | |
| SCHEMBL23132466 | 0.84 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDMAPTNPSR1 | |
| SCHEMBL19439513 | 0.84 | CYP1A1 (0.35) | ALDH1A1HPGDMAPTLMNANPY1R | |
| SCHEMBL18876850 | 0.83 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535619-B2 | Hexacyclic heteroaromatic compounds for electronic devices | MERCK PATENT GMBH (DE) | 2022-12-27 | — | — | US | disclosed |
| US-20220216424-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-07-07 | — | — | US | disclosed |
| US-20220162205-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-05-26 | — | — | US | disclosed |
| EP-3630764-B1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR USE IN ELEKTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-08-18 | — | — | EP | disclosed |
| EP-3583104-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-06-09 | — | — | EP | disclosed |
| US-10923665-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2021-02-16 | — | — | US | disclosed |
| US-20200165252-A1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-05-28 | — | — | US | disclosed |
| US-20200044162-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162205-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | OR10J3, EPCAM, L1CAM | ALDH1A1 473/4885KDM4E 1889/4885HPGD 1503/4885 |
| US-10923665-B2 | Materials for organic electroluminescent devices | OR10J3, L1CAM, EPCAM | ALDH1A1 441/4885KDM4E 1917/4885HPGD 1551/4885 |
| US-20200165252-A1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR ELECTRONIC DEVICES | ETV6, CYP2J2, CYP2D6 | ALDH1A1 647/4885KDM4E 2237/4885HPGD 209/4885 |
| US-20220216424-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | OR10J3, EPCAM, L1CAM | ALDH1A1 473/4885KDM4E 1889/4885HPGD 1503/4885 |
| US-11535619-B2 | Hexacyclic heteroaromatic compounds for electronic devices | ETV6, CYP2J2, CYP2D6 | ALDH1A1 647/4885KDM4E 2237/4885HPGD 209/4885 |
| US-20200044162-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | OR10J3, L1CAM, EPCAM | ALDH1A1 441/4885KDM4E 1917/4885HPGD 1551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.