Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.72 |
| ▸ | REN | P00797 | 4/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | F2 | P00734 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | LTA4H | P09960 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | PEPD | P12955 | 1/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.72 |
| ▸ | HTR2A | P28223 | 1/20 | 0.72 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.72 |
| ▸ | HRH1 | P35367 | 1/20 | 0.72 |
| ▸ | THPO | P40225 | 1/20 | 0.72 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19362588 | 1.00 | ACE (0.72) | ACERENKDM4EF2LMNA | |
| SCHEMBL10802283 | 1.00 | ACE (0.72) | ACERENKDM4EF2LMNA | |
| SCHEMBL10856632 | 1.00 | ACE (0.72) | ACERENKDM4EF2LMNA | |
| SCHEMBL6788721 | 0.87 | ACE (0.77) | ACERENKDM4EF2LMNA | |
| SCHEMBL6788727 | 0.87 | ACE (0.77) | ACERENKDM4EF2LMNA | |
| SCHEMBL6788835 | 0.87 | ACE (0.85) | ACERENKDM4EF2LMNA | |
| SCHEMBL12680174 | 0.85 | ACE (0.74) | ACERENKDM4EF2LMNA | |
| SCHEMBL29426304 | 0.85 | ACE (0.74) | ACERENKDM4EF2LMNA | |
| SCHEMBL15223628 | 0.85 | ACE (0.74) | ACERENKDM4EF2LMNA | |
| SCHEMBL19235752 | 0.85 | ACE (0.74) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020028593-A9 | A METHOD OF TREATING ER MUTANT EXPRESSING BREAST CANCERS WITH SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | Oncternal Therapeutics, Inc. (US) | 2021-03-18 | — | — | WO | disclosed |
| WO-2020028593-A1 | A METHOD OF TREATING ER MUTANT EXPRESSING BREAST CANCERS WITH SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | Oncternal Therapeutics, Inc. (US) | 2020-02-06 | — | — | WO | disclosed |
| CN-103086940-B | Synthetic method of 1-(3-mercapto-2-D-methyl propionyl)-L-proline | HUAZHONG PHARMACEUTICAL CO LTD | 2014-07-09 | — | — | CN | disclosed |
| CN-103086940-A | Synthetic method of 1-(3-mercapto-2-D-methyl propionyl)-L-proline | HUAZHONG PHARMACEUTICAL CO LTD | 2013-05-08 | — | — | CN | disclosed |
| CN-103086939-A | Recrystallization method of 1-(3-bromo-2-D-methyl propionyl)pyrrolidine-2-carboxylic acid | HUAZHONG PHARMACEUTICAL CO LTD | 2013-05-08 | — | — | CN | disclosed |
| CN-103086939-A | Recrystallization method of 1-(3-bromo-2-D-methyl propionyl)pyrrolidine-2-carboxylic acid | HUAZHONG PHARMACEUTICAL CO LTD | 2013-05-08 | — | — | CN | disclosed |