Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.88 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.88 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | CRHBP | P24387 | 2/20 | 0.63 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21644442 | 0.84 | L3MBTL1 (0.75) | NPSR1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL21644441 | 0.84 | L3MBTL1 (0.75) | NPSR1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL28581411 | 0.81 | L3MBTL1 (0.67) | NPSR1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL28581410 | 0.81 | L3MBTL1 (0.67) | NPSR1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18194711 | 0.80 | NPSR1 (0.66) | NPSR1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL19381680 | 0.79 | MAPT (0.63) | NPSR1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5704500 | 0.78 | CYP19A1 (0.62) | NPSR1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL2169670 | 0.78 | KMT2A (0.65) | NPSR1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL23786250 | 0.77 | MAPT (0.69) | NPSR1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL8607686 | 0.77 | MAPT (0.69) | NPSR1L3MBTL1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020028724-A1 | SUBSTITUTED-3H-IMIDAZO[4,5-C]PYRIDINE AND 1H-PYRROLO[2,3-C]PYRIDINE SERIES OF NOVEL ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE-1 (ENPP1) AND STIMULATOR FOR INTERFERON GENES (STING) MODULATORS AS CANCER IMMUNOTHERAPEUTICS | Stingray Therapeutics, Inc. (US) | 2020-02-06 | — | — | WO | disclosed |