Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18591825 | 0.90 | HSD11B1 (0.35) | HSD11B1CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL23664612 | 0.80 | HSD11B1 (0.35) | HSD11B1CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL24654303 | 0.79 | HSD11B1 (0.35) | HSD11B1CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL18551233 | 0.71 | HSD11B1 (0.45) | HSD11B1CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL20234787 | 0.70 | ALDH2 (0.37) | — | |
| SCHEMBL18551310 | 0.70 | HSD11B1 (0.44) | HSD11B1CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL13701768 | 0.69 | EPHX2 (0.42) | EPHX2 | |
| SCHEMBL20330004 | 0.68 | SLC6A2 (0.41) | — | |
| SCHEMBL13876020 | 0.68 | EPHX2 (0.40) | EPHX2 | |
| SCHEMBL18591736 | 0.66 | AKT1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200038513-A1 | MODULATORS OF FAK PROTEOLYSIS AND ASSOCIATED METHODS OF USE | YALE UNIVERSITY | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200038513-A1 | MODULATORS OF FAK PROTEOLYSIS AND ASSOCIATED METHODS OF USE | PTK2, CTTN, CRBN | HSD11B1 4719/4885CYP2C19 4870/4885CYP3A4 4853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.