SCHEMBL2166705

SCHEMBL2166705

CCCCc1c(O)ccc(Cl)c1C

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.46
NPC1 O15118 1/20 0.46
HPGD P15428 1/20 0.46
HTT P42858 1/20 0.46
RAB9A P51151 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TYR P14679 2/20 0.43
CFTR P13569 4/20 0.39
KDM4E B2RXH2 1/20 0.39
PKM P14618 1/20 0.39
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
IGF1R P08069 1/20 0.37
ALOX15 P16050 1/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CYP3A4 P08684 1/20 0.35
AR P10275 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2168406 0.93 TYR (0.53) HTTTYRKDM4EESR1ALOX15
SCHEMBL875815 0.90 CNR1 (0.38) MAPK1NPC1HPGDHTTRAB9A
SCHEMBL7950540 0.84 TYR (0.53) MAPK1NPC1HPGDHTTRAB9A
SCHEMBL664026 0.82 CYP3A4 (0.39) MAPK1HPGDKDM4EESR1ESR2
SCHEMBL30026986 0.81 HPGD (0.58) MAPK1NPC1HPGDHTTRAB9A
SCHEMBL710654 0.81 HPGD (0.58) MAPK1NPC1HPGDHTTRAB9A
SCHEMBL6232725 0.81 HPGD (0.46) MAPK1NPC1HPGDHTTRAB9A
SCHEMBL30945773 0.80 HPGD (0.48) MAPK1NPC1HPGDHTTRAB9A
SCHEMBL983815 0.80 HPGD (0.48) MAPK1NPC1HPGDHTTRAB9A
SCHEMBL10636865 0.79 TYR (0.46) MAPK1NPC1HPGDHTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3528776-B1 REDUCED-ETHANOL MOUTH RINSE FORMULATIONS KENVUE BRANDS LLC (US) 2025-11-26 EP disclosed
EP-3653303-B1 PIPETTE TIP RACK BIOTIX INC (US) 2025-02-26 EP disclosed
US-12201987-B2 Pipette tip rack BIOTIX, INC. (US) 2025-01-21 US disclosed
US-11857653-B2 Method of providing an oral care benefit using a poorly-soluble calcium compound and fluoride JOHNSON & JOHNSON CONSUMER INC. (US) 2024-01-02 US disclosed
US-11648186-B2 Coated particles and their uses JOHNSON & JOHNSON CONSUMER INC. (US) 2023-05-16 US disclosed
US-11590490-B2 Pipette tips BIOTIX, INC. (US) 2023-02-28 US disclosed
US-20220331222-A1 Method of Providing Oral Care Benefits KENVUE BRANDS LLC 2022-10-20 US disclosed
US-20220226205-A1 Coated Particles and Their Uses KENVUE BRANDS LLC 2022-07-21 US disclosed
US-11351103-B2 Method of providing oral care benefits JOHNSON & JOHNSON CONSUMER INC. (US) 2022-06-07 US disclosed
US-11291613-B2 Coated particles and their uses JOHNSON & JOHNSON CONSUMER INC. (US) 2022-04-05 US disclosed
US-5686064-A MIXTURE INCLUDES TETRAALKALI METAL POLYPHOSPHATE AND TRICLOSAN; DENTIFRICES COLGATE PALMOLIVE COMPANY (US) 1997-11-11 US disclosed
US-5681548-A CONTAINING AMPHOTERIC SURFACTANT AND MICROBIOCIDE COLGATE PALMOLIVE COMPANY (US) 1997-10-28 US disclosed
US-5599526-A HAVING ANIONIC SURFACTANT CONTAINING A POLYOXYETHYLE ALCOHOL SULFATE AND/OR ALKALI LAURYL SULFATE, OR MIXTURE OF ALKALI LAURYL SULFATE AND AN N-ACYL-N-ALKYLTAURATE; NONCRYSTALLIZING AT LOW TEMPERTURES COLGATE-PALMOLIVE COMPANY 1997-02-04 US disclosed
US-5575652-A Process for applying antibacterial oral composition to dental implant areas COLGATE PALMOLIVE COMPANY (US) 1996-11-19 US disclosed
US-5538715-A DENTIFRICES WITH ANTIPLAQUE AGENTS FOR MOUTHS WITH HUMECTANTS, SILICA POLISHES AND BACTERICIDES COLGATE PALMOLIVE COMPANY (US) 1996-07-23 US disclosed
US-5288480-A Antiplaque antibacterial oral composition COLGATE-PALMOLIVE CO. (US) 1994-02-22 US disclosed
US-5192530-A Solubilizer, enhancing agent to aid retention, and delivery enhancement COLGATE-PALMOLIVE COMPANY (US) 1993-03-09 US disclosed
US-5178851-A Dentifrices treatment with triclosan and carriers COLGATE-PALMOLIVE COMPANY (US) 1993-01-12 US disclosed
US-5080887-A Polyphosphate, bactericide COLGATE-PALMOLIVE COMPANY (US) 1992-01-14 US disclosed
US-4894220-A WATER AND ALCOHOL SOLVENTS, GLYCOL DERIVATIVES AND ESTERS SOLUTIONS COLGATE-PALMOLIVE COMPANY (US) 1990-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11291613-B2 Coated particles and their uses CD63, EPCAM, CD44 MAPK1 4711/4885NPC1 2820/4885HPGD 3992/4885
US-11648186-B2 Coated particles and their uses CD63, EPCAM, CD44 MAPK1 4711/4885NPC1 2820/4885HPGD 3992/4885
US-20220226205-A1 Coated Particles and Their Uses CD63, EPCAM, CD44 MAPK1 4711/4885NPC1 2820/4885HPGD 3992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.