Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21669762 | 1.00 | TBXAS1 (0.51) | TBXAS1SMN1; SMN2LMNAGAAL3MBTL1 | |
| SCHEMBL21669764 | 1.00 | TBXAS1 (0.51) | TBXAS1SMN1; SMN2LMNAGAAL3MBTL1 | |
| SCHEMBL21669742 | 1.00 | TBXAS1 (0.51) | TBXAS1SMN1; SMN2LMNAGAAL3MBTL1 | |
| SCHEMBL21669760 | 1.00 | TBXAS1 (0.51) | TBXAS1SMN1; SMN2LMNAGAAL3MBTL1 | |
| SCHEMBL21669758 | 0.99 | SMN1; SMN2 (0.50) | TBXAS1SMN1; SMN2LMNAGAAL3MBTL1 | |
| SCHEMBL2600106 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAGAAL3MBTL1PKM | |
| SCHEMBL27241501 | 0.86 | TBXAS1 (0.56) | TBXAS1LMNATSHRMAPK1 | |
| SCHEMBL21669740 | 0.85 | TBXAS1 (0.54) | TBXAS1SMN1; SMN2LMNAGAAL3MBTL1 | |
| SCHEMBL21669744 | 0.85 | TBXAS1 (0.54) | TBXAS1SMN1; SMN2LMNAGAAL3MBTL1 | |
| SCHEMBL21669751 | 0.85 | TBXAS1 (0.54) | TBXAS1SMN1; SMN2LMNAGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3077476-B1 | NANOCRYSTALS COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF | NEXDOT (FR) | 2020-02-12 | — | — | EP | disclosed |