Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21670281 | 1.00 | TP53 (0.54) | TP53MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL21670280 | 0.91 | SMN1; SMN2 (0.62) | MEN1KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL21669775 | 0.91 | SMN1; SMN2 (0.62) | MEN1KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL21669811 | 0.88 | LMNA (0.59) | TP53MEN1KMT2ALMNAGAA | |
| SCHEMBL21670309 | 0.88 | LMNA (0.59) | TP53MEN1KMT2ALMNAGAA | |
| SCHEMBL21669813 | 0.85 | TP53 (0.56) | TP53MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL21670501 | 0.85 | TP53 (0.56) | TP53MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL21669810 | 0.83 | MAPT (0.62) | TP53MEN1KMT2ALMNAGAA | |
| SCHEMBL21669865 | 0.83 | MAPT (0.62) | TP53MEN1KMT2ALMNAGAA | |
| SCHEMBL21670294 | 0.82 | EPHX2 (0.64) | LMNASMN1; SMN2MAPTNPSR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020028482-A1 | SMALL MOLECULES THAT SENSITIZE HIV-1 INFECTED CELLS TO ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2020-02-06 | — | — | WO | disclosed |