Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 9/20 | 0.72 |
| ▸ | MMP1 | P03956 | 3/20 | 0.64 |
| ▸ | FCER2 | P06734 | 3/20 | 0.64 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | CPA1 | P15085 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.50 |
| ▸ | TACR2 | P21452 | 1/20 | 0.49 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14485921 | 1.00 | KLKB1 (0.72) | KLKB1MMP1FCER2MMEACE | |
| SCHEMBL17268025 | 1.00 | KLKB1 (0.72) | KLKB1MMP1FCER2MMEACE | |
| SCHEMBL15901046 | 0.89 | KLKB1 (0.77) | KLKB1MMP1FCER2 | |
| SCHEMBL14485892 | 0.89 | KLKB1 (0.77) | KLKB1MMP1FCER2 | |
| SCHEMBL21669886 | 0.87 | KLKB1 (0.83) | KLKB1MMP1FCER2MMEACE | |
| SCHEMBL21669883 | 0.87 | KLKB1 (0.72) | KLKB1MMP1FCER2 | |
| SCHEMBL14485287 | 0.87 | KLKB1 (0.72) | KLKB1MMP1FCER2 | |
| SCHEMBL21669870 | 0.87 | KLKB1 (0.69) | KLKB1MMP1FCER2MMEACE | |
| SCHEMBL15901681 | 0.87 | KLKB1 (0.69) | KLKB1MMP1FCER2MMEACE | |
| SCHEMBL14485442 | 0.87 | KLKB1 (0.83) | KLKB1MMP1FCER2MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729443-B3 | BENZYLAMINE DERIVATIVES AS INHIBITORS OF PLASMA KALLIKREIN | KALVISTA PHARMACEUTICALS LTD (GB) | 2020-02-12 | — | — | EP | disclosed |