Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.33 |
| ▸ | FDPS | P14324 | 9/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24854979 | 0.96 | DNM1 (0.41) | DNM1TSHRTHRBGGPS1FDPS | |
| Hydrochloric Acid SCHEMBL29102035 | 0.89 | DNM1 (0.46) | DNM1TSHRTHRBGGPS1FDPS | |
| SCHEMBL23084861 | 0.89 | DNM1 (0.37) | DNM1TSHRTHRBGGPS1FDPS | |
| SCHEMBL23377631 | 0.87 | DNM1 (0.36) | DNM1TSHRTHRBGGPS1FDPS | |
| SCHEMBL24368445 | 0.83 | DNM1 (0.46) | DNM1TSHRFDPSSMPD1 | |
| SCHEMBL21941313 | 0.83 | DNM1 (0.46) | DNM1TSHRFDPSSMPD1 | |
| SCHEMBL21179492 | 0.81 | TSHR (0.42) | DNM1TSHRTHRBGGPS1FDPS | |
| SCHEMBL18722279 | 0.81 | TSHR (0.42) | DNM1TSHRTHRBGGPS1FDPS | |
| SCHEMBL28460650 | 0.81 | TSHR (0.42) | DNM1TSHRTHRBGGPS1FDPS | |
| SCHEMBL28521973 | 0.81 | TSHR (0.42) | DNM1TSHRTHRBGGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200039943-A1 | COMPOUNDS, DEVICES, AND USES THEREOF | SIGILON THERAPEUTICS, INC. | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039943-A1 | COMPOUNDS, DEVICES, AND USES THEREOF | SLC10A1, SLCO1B3, SLC5A1 | DNM1 4354/4885TSHR 2004/4885THRB 439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.