Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5022233 | 1.00 | TSHR (0.62) | TSHRALDH1A1MAPK1GAACYP2C19 | |
| SCHEMBL6968129 | 0.89 | TP53 (0.53) | TSHRALDH1A1MAPK1GAACYP2C19 | |
| Hydrochloric Acid SCHEMBL17510088 | 0.87 | TP53 (0.51) | TSHRALDH1A1MAPK1GAACYP2C19 | |
| SCHEMBL21670255 | 0.84 | TSHR (0.53) | TSHRALDH1A1MAPK1KMT2ACYP1A2 | |
| SCHEMBL21670252 | 0.84 | TSHR (0.64) | TSHRALDH1A1MAPK1GAACYP2C19 | |
| SCHEMBL1439777 | 0.84 | TSHR (0.64) | TSHRALDH1A1MAPK1GAACYP2C19 | |
| SCHEMBL9949812 | 0.84 | TSHR (0.64) | TSHRALDH1A1MAPK1GAACYP2C19 | |
| SCHEMBL14009862 | 0.84 | TSHR (0.64) | TSHRALDH1A1MAPK1GAACYP2C19 | |
| SCHEMBL9949602 | 0.84 | TSHR (0.64) | TSHRALDH1A1MAPK1GAACYP2C19 | |
| SCHEMBL4669397 | 0.81 | ALDH1A1 (0.59) | TSHRALDH1A1MAPK1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020028482-A1 | SMALL MOLECULES THAT SENSITIZE HIV-1 INFECTED CELLS TO ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2020-02-06 | — | — | WO | disclosed |