Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21670265 | 0.88 | LMNA (0.66) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL21670264 | 0.82 | LMNA (0.62) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL25681987 | 0.79 | KMT2A (0.72) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12245070 | 0.79 | LMNA (0.67) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL26899815 | 0.78 | NPC1 (0.47) | LMNAMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL14400305 | 0.78 | LMNA (0.54) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL19198292 | 0.77 | SMN1; SMN2 (0.64) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11691670 | 0.76 | MEN1 (0.72) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9324598 | 0.76 | MEN1 (0.72) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL18882713 | 0.76 | MEN1 (0.72) | LMNAMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020028482-A1 | SMALL MOLECULES THAT SENSITIZE HIV-1 INFECTED CELLS TO ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2020-02-06 | — | — | WO | disclosed |