Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.42 |
| ▸ | NQO2 | P16083 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21670328 | 1.00 | ESR1 (0.53) | ESR1ESR2PTGS2PTGS1NQO2 | |
| SCHEMBL13668363 | 0.83 | TP53 (0.44) | PTGS2TP53SCN1ASCN2ASCN3A | |
| SCHEMBL28426802 | 0.76 | AKR1C3 (0.55) | PTGS2TP53SCN1ASCN2ASCN3A | |
| SCHEMBL26750838 | 0.76 | NR4A1 (0.50) | PTGS2TP53SCN1ASCN2ASCN3A | |
| SCHEMBL13653950 | 0.73 | NOS3 (0.53) | PTGS2TP53SCN1ASCN2ASCN3A | |
| SCHEMBL23854165 | 0.72 | CA1 (0.47) | PTGS2TP53SCN1ASCN2ASCN3A | |
| SCHEMBL13882617 | 0.72 | CA1 (0.47) | PTGS2TP53SCN1ASCN2ASCN3A | |
| SCHEMBL27641560 | 0.71 | TP53 (0.36) | PTGS2TP53SCN1ASCN2ASCN3A | |
| SCHEMBL1404353 | 0.71 | ESR1 (0.53) | ESR1ESR2PTGS2PTGS1NQO2 | |
| SCHEMBL1404352 | 0.71 | ESR1 (0.53) | ESR1ESR2PTGS2PTGS1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3606650-A1 | THIN FILM COMPOSITE MEMBRANE INCLUDING CROSSLINKED TROGER'S BASE POLYMER | Dow Global Technologies LLC (US) | 2020-02-12 | — | — | EP | disclosed |