Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2877876 | 0.88 | SLC22A12 (0.35) | KMT2AMEN1SLC22A12 | |
| SCHEMBL188869 | 0.87 | F2RL3 (0.36) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL188969 | 0.84 | MEN1 (0.34) | KMT2AMEN1 | |
| SCHEMBL188536 | 0.84 | MEN1 (0.36) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL218961 | 0.83 | MEN1 (0.33) | PPARGKMT2AMEN1 | |
| SCHEMBL219010 | 0.83 | MEN1 (0.37) | KMT2AMEN1ALDH1A1HSD17B10GAA | |
| SCHEMBL2875942 | 0.83 | MEN1 (0.37) | KMT2AMEN1GAA | |
| SCHEMBL216006 | 0.83 | POLB (0.40) | KMT2AMEN1ALDH1A1KDM4EALOX15 | |
| SCHEMBL218024 | 0.82 | CSF1R (0.35) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL188485 | 0.81 | MEN1 (0.40) | KMT2AMEN1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401281-A1 | PYRIMIDOPYRIMIDOINDAZOLE DERIVATIVE | MSD K.K. (JP) | 2012-01-04 | — | — | EP | disclosed |