SCHEMBL21670542

SCHEMBL21670542

COc1ccccc1-c1cc(-c2ccc(Nc3ccccc3)cc2)cc(-c2ccccc2)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STK10 O94804 2/20 0.49
SLK Q9H2G2 2/20 0.49
LMNA P02545 5/20 0.46
USP2 O75604 3/20 0.46
ALDH1A1 P00352 3/20 0.46
CYP1A2 P05177 3/20 0.46
CYP2D6 P10635 3/20 0.46
CYP2C19 P33261 3/20 0.46
CLK4 Q9HAZ1 2/20 0.46
TSHR P16473 2/20 0.46
CYP3A4 P08684 2/20 0.46
CYP2C9 P11712 1/20 0.46
HSD17B10 Q99714 3/20 0.46
ALOX15 P16050 2/20 0.46
ADORA3 P0DMS8 1/20 0.46
VCP P55072 2/20 0.45
HPGDS O60760 1/20 0.45
DHODH Q02127 1/20 0.44
ACP1 P24666 1/20 0.44
HPGD P15428 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30525998 1.00 STK10 (0.49) STK10SLKLMNAUSP2ALDH1A1
SCHEMBL21670529 0.96 CYP1A2 (0.49) STK10SLKLMNAUSP2ALDH1A1
SCHEMBL6264546 0.88 AGPAT2 (0.50) STK10SLKLMNAUSP2ALDH1A1
SCHEMBL30526044 0.84 ACP1 (0.48) STK10SLKLMNAUSP2ALDH1A1
SCHEMBL29048668 0.84 ACP1 (0.48) STK10SLKLMNAUSP2ALDH1A1
SCHEMBL21670575 0.84 ACP1 (0.48) STK10SLKLMNAUSP2ALDH1A1
SCHEMBL21670539 0.84 ADORA2A (0.45) LMNAUSP2ALDH1A1CYP1A2CYP2D6
SCHEMBL30525993 0.84 ADORA2A (0.45) LMNAUSP2ALDH1A1CYP1A2CYP2D6
SCHEMBL21670541 0.83 MEN1 (0.52) ALDH1A1CYP1A2CYP2D6CYP2C19CYP3A4
SCHEMBL30525969 0.83 MEN1 (0.52) ALDH1A1CYP1A2CYP2D6CYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3608386-B1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN PILOT INK CO LTD (JP) 2025-02-19 EP disclosed
CN-110446770-B Reversible thermochromic composition and reversible thermochromic microcapsule pigment containing the same 百乐墨水株式会社 2023-08-08 CN disclosed
US-11060018-B2 Reversibly thermochromic composition and reversibly thermochromic microcapsule pigment encapsulating the same THE PILOT INK CO., LTD. (JP) 2021-07-13 US disclosed
US-20200048542-A1 REVERSIBLY THERMOCHROMIC COMPOSITION AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING THE SAME THE PILOT INK CO., LTD. (JP) 2020-02-13 US disclosed
EP-3608386-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN The Pilot Ink Co., Ltd (JP) 2020-02-12 EP disclosed
CN-110446770-A Reversible thermal discoloration composition and reversible thermal discoloration microcapsule pigment containing the same PILOT INK CO LTD 2019-11-12 CN disclosed